Clinical Application and Outcome of Non-invasive Ventilation in Different Chest Diseases

Chest--Diseases Clinical Trial

Official title:

Clinical Application and Outcome of Non-invasive Ventilation in Different Chest Diseases

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT03169452
• Other study ID #: NIV
• Status: Recruiting
• Start date: June 1, 2017
• Est. completion date: November 2018

Study information

• Verified date: June 2018
• Source: Assiut University
• Contact: Sahar Mohamed, MBBCh
• Phone: 00201069916415
• Email: saharmuhammad25[@]yahoo.com
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Noninvasive ventilation is increasingly used method of respiratory management in both the emergency room and critical care. Noninvasive ventilation delivers mechanically assisted breaths without the placement of an artificial airway and has become an important mechanism of ventilator support inside and outside the intensive care unit.

Noninvasive ventilation is further subdivided into negative pressure ventilation which is the iron lung, first used in 1928 and the Hayek oscillator, is a more recently designed to provide negative pressure during inspiration and positive pressure during expiration. Noninvasive positive pressure ventilation can be used as continuous positive airway pressure or bi-level positive airway pressure.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 150
• Est. completion date: November 2018
• Est. primary completion date: August 2018
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• obstructive sleep apnea syndrome

• acute exacerbation Chronic obstructive pulmonary disease

• pneumonia

• interstitial lung diseases

Exclusion Criteria:

• Patients refuse Non invasive ventilation

• Patients with absolute indication for Mechanical ventilator (in respiratory arrest or unstable cardiorespiratory status, trauma or burns involving the face, or gastric surgery, reduced consciousness, Pneumothorax

• Patients with contraindication to Non invasive ventilation

Related Conditions & MeSH terms

• Chest--Diseases

Intervention

Device:
• Non-invasive mechanical ventilator
mechanical assisted breaths without the placement of an artificial way

Locations

Country	Name	City	State
Egypt	Assiut University	Assiut

Sponsors (1)

Lead Sponsor	Collaborator
Assiut University

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	percentage of patients need mechanical ventilation	the number of patients without improvement on non-invasive ventilator and require transfer to mechanical ventilator	1-48 hours