Clinical Trials Logo

Clinical Trial Summary

There are no standard chemotherapy regimens for relapse/refractory gray area lymphoma. The programmed cell death ligand 1 (PD-L1) encoding gene is located in 9p24.1, so it is speculated that the programmed cell death pathway plays an important role in gray area lymphoma formation by evading immune surveillance in GZL.The purpose of this study was to evaluate the efficacy and safety of PD-1 monoclonal antibody combined with ICE in the treatment of patients with relapsed/refractory gray area lymphoma.


Clinical Trial Description

The purpose of this study was to evaluate the efficacy and safety of PD-1 monoclonal antibody combined with ICE in the treatment of patients with relapsed/refractory gray zone lymphoma. The main study endpoint is the Objective Response Rate (ORR), including Complete Remission Rate (CRR) and Partial Remission Rate (PRR), was evaluated according to Lugano2014 lymphoma efficacy evaluation criteria. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04860674
Study type Interventional
Source Zhejiang Cancer Hospital
Contact Cong Li
Phone 15267115611
Email [email protected]
Status Not yet recruiting
Phase Phase 2
Start date May 1, 2021
Completion date April 1, 2024

See also
  Status Clinical Trial Phase
Active, not recruiting NCT03753542 - Effect of Nurse-led Education on Parent's Anxiety and Depression on Managing Side Effects of Chemotherapy N/A
Recruiting NCT04207359 - Effects of Creatine Supplementation in Breast Cancer Survivors N/A
Recruiting NCT04173195 - Comfort Talk (CT) During Outpatient Chemotherapy N/A
Recruiting NCT03275194 - HIPEC in Ovarian Carcinoma Clinical Stage IIIC and IV During Interval Laparotomy Phase 2
Not yet recruiting NCT04065139 - Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC) in Gastric Carcinomatosis. Phase II Randomized Study Phase 2
Completed NCT04118322 - The Effect of Peppermint Oil on Nausea, Vomiting and Retching in Cancer Patients Undergoing Chemotherapy N/A
Not yet recruiting NCT04845490 - Comparative Study of Mitomycin and Lobaplatin in Advanced Colorectal Cancer Patients With Radical Surgery Combined With Hyperthermic Intraperitoneal Chemotherapy Phase 2
Not yet recruiting NCT04808466 - Comparative Study of Lobaplatin and Paclitaxel in Advanced Gastric Cancer Patients With D2 Surgery Combined With Hyperthermic Intraperitoneal Chemotherapy Phase 2
Enrolling by invitation NCT04027478 - Can Fasting Decrease the Side Effects of Chemotherapy? N/A
Completed NCT04116138 - Antisecretory Factor in Primary Glioblastoma 1 Phase 1/Phase 2
Recruiting NCT03683407 - Effect of Chemotherapy on TMB in NSCLC
Completed NCT03078608 - POEM (Practice Of Embracing Each Moment) STUDY N/A
Recruiting NCT03562234 - The CLiFF Study: Change in Liver Function and Fat in Pre-operative Chemotherapy for Colorectal Liver Metastases
Recruiting NCT03689478 - Use of Immediate Hyperthermic Intravesical Chemotherapy Following TURBT Phase 1
Recruiting NCT04636255 - Physical Capacity in Hodgkin Lymphoma Survivors N/A
Recruiting NCT04150393 - Safety and Tolerability Evaluation of MaaT033 Phase 1
Recruiting NCT04649567 - COLONIC RESECTION FOR CANCER AS DIABETOGENIC RISK FACTOR
Active, not recruiting NCT03668496 - A Study of SHR-1210 in Combination With Carboplatin + Paclitaxel in Subjects With Squamous NSCLC Phase 3
Recruiting NCT03253107 - Predicting Biomarker of Gastric Cancer Chemotherapy Response
Not yet recruiting NCT03341286 - The Effect of an Oral Supplement,TK3 (Tryptophan and Thiamine) on the Quality of Life and Chemotherapy Tolerance in Cancer Patients With Advanced Disease. Phase 2