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Intraperitoneal and System Chemotherapy Versus XELOX as First-line Chemotherapy for mCRC

Chemotherapy Effect Clinical Trial

Official title:
An Open-label, Randomized, Phase II Clinical Trial Comparing the Efficacy and Safety of Intraperitoneal and System Chemotherapy Versus XELOX as First-line Chemotherapy for Metastatic Colorectal Cancer

Clinical Trial Summary

XELOX as first-line treatment regimen has limited efficacy against patients with metastatic colorectal cancer (mCRC). Peritoneal metastasis is one of the most lethal factor for mCRC. Intraperitoneal chemotherapy has became a widely accepted strategy in the treatment of peritoneal dissemination. We hypothesized that combined multi-channel administration, such as intraperitoneal chemotherapy, oral chemotherapy, and intravenous chemotherapy, can produce better results than XELOX for first-line treatment for mCRC patients.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03792269
Study type Interventional
Source The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Contact Jing Hu, M.D., P.hD
Phone 0086-13057668736
Email doctorhujing@hotmail.com
Status Recruiting
Phase Phase 2
Start date January 1, 2016
Completion date December 2020
View Details
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