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Clinical Trial Summary

Charcot neuroarthropathy (CN) is a debilitating disease primarily affecting poorly controlled diabetic patients with peripheral neuropathy. The consequences of CN include ulcerations of the foot and ankle, osteomyelitis, and severe musculoskeletal deformity. These consequences frequently lead to below-knee amputation of the affected limb.

Currently treatment options are limited, and no pharmaceutical treatment has been efficacious in the medical literature. The purpose of this pilot study is to investigate the potential of the medication denosumab for acute stage Charcot neuroarthropathy.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT03174366
Study type Interventional
Source Western University of Health Sciences
Contact
Status Completed
Phase Phase 3
Start date May 16, 2017
Completion date March 6, 2019

See also
  Status Clinical Trial Phase
Completed NCT05797259 - RANKL Antibody for Acute Charcot Neuro-osteoarthropathy Phase 4
Recruiting NCT05491577 - Factors Associated With an Evolution in the Quality of Life of Diabetic Patients With Chronic, Wound-free Charcot Foot
Completed NCT04668755 - Effect of CROW 3d Printed Sole on Charcot Foot Ulcer N/A