Cell Therapy in Chagas Cardiomyopathy

Status Terminated

Clinical Trial Summary

The purpose of this study is to determine effect of cell therapy in patients with severe dilated cardiomyopathy

Clinical Trial Description

This protocol describes a double-blind placebo controlled randomized clinical trial to evaluate the efficacy of bone marrow derived stem cell implants in 300 bazillion patients with dilated cardiomyopathy and heart failure in class III or IV of the New York Heart Association.

The primary endpoint of this study is to evaluate the effect of the autologous bone marrow stem cell implant in the increase of the ejection fraction of the left ventricle in comparison with a control group, under optimized therapy for dilated cardiomyopathy. Secondary endpoints will evaluate the alteration in NYHA functional class, mortality rate, physical capacity (by ergoespirometry), life quality (Minnesota questionnaire) and pulmonary congestion in dilated cardiomyopathy patients the received the autologous bone-marrow stem cell implant. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT00349271
Study type	Interventional
Source	Ministry of Health, Brazil
Contact
Status	Terminated
Phase	Phase 3
Start date	January 2006
Completion date	December 2011

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See also
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