Frailty in Critical Care Unit's Patients

CFS Clinical Trial

Official title:

Frailty in Critical Care Unit's Patients

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT06117462
• Other study ID #: Fraility in CCU
• Status: Not yet recruiting
• Start date: December 2023
• Est. completion date: December 2024

Study information

• Verified date: November 2023
• Source: Assiut University
• Contact: Doaa Mostafa Ibrahim
• Phone: 01141896238
• Email: doaamostafa299[@]gmail.com
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

In the study ,investigator aim to evaluate the frailty syndrome in critically ill patients, in both young and old populations,to determine its imapct on outcome, and impact of ICU in fraility

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 116
• Est. completion date: December 2024
• Est. primary completion date: December 2024
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• All ICU patients >18 years

Exclusion Criteria:

• Age <18 years

Related Conditions & MeSH terms

• CFS
• Frailty

Intervention

Other:
• Assesment of CFS
Assesment of CFS

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Assiut University

References & Publications (5)

Darvall JN, Bellomo R, Bailey M, Young PJ, Rockwood K, Pilcher D. Impact of frailty on persistent critical illness: a population-based cohort study. Intensive Care Med. 2022 Mar;48(3):343-351. doi: 10.1007/s00134-022-06617-0. Epub 2022 Feb 4. — View Citation

de Rooij SE, Govers A, Korevaar JC, Abu-Hanna A, Levi M, de Jonge E. Short-term and long-term mortality in very elderly patients admitted to an intensive care unit. Intensive Care Med. 2006 Jul;32(7):1039-44. doi: 10.1007/s00134-006-0171-0. Epub 2006 May 9. — View Citation

Guidet B, de Lange DW, Boumendil A, Leaver S, Watson X, Boulanger C, Szczeklik W, Artigas A, Morandi A, Andersen F, Zafeiridis T, Jung C, Moreno R, Walther S, Oeyen S, Schefold JC, Cecconi M, Marsh B, Joannidis M, Nalapko Y, Elhadi M, Fjolner J, Flaatten H; VIP2 study group. The contribution of frailty, cognition, activity of daily life and comorbidities on outcome in acutely admitted patients over 80 years in European ICUs: the VIP2 study. Intensive Care Med. 2020 Jan;46(1):57-69. doi: 10.1007/s00134-019-05853-1. Epub 2019 Nov 29. — View Citation

Liu Z, Kuo PL, Horvath S, Crimmins E, Ferrucci L, Levine M. A new aging measure captures morbidity and mortality risk across diverse subpopulations from NHANES IV: A cohort study. PLoS Med. 2018 Dec 31;15(12):e1002718. doi: 10.1371/journal.pmed.1002718. eCollection 2018 Dec. Erratum In: PLoS Med. 2019 Feb 25;16(2):e1002760. — View Citation

Muscedere J, Waters B, Varambally A, Bagshaw SM, Boyd JG, Maslove D, Sibley S, Rockwood K. The impact of frailty on intensive care unit outcomes: a systematic review and meta-analysis. Intensive Care Med. 2017 Aug;43(8):1105-1122. doi: 10.1007/s00134-017-4867-0. Epub 2017 Jul 4. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	detect the impact of frailty on outcome(hospital stay and mortality).In Critical care units patients.	evaluate the frailty syndrome in critical care unit ,in young and old populations.CFS will report patient's basal score[ pre intervention] on day of admission and the outcome score at day of discharge [5day],score 1better than higher	the CFS before hospital admission and at day up to 1 week of discharge from CCU, CFS mininum 1 ,maximum 9 patient's basal score[ pre intervention] on day of admission and the outcome score at day of discharge [5day],score 1better than higher