Cesarean Section Clinical Trial
Official title:
Role of Co-administered Dexamethasone in Transversus Abdominis Plane Block After Cesarean Section: A Randomized, Double-blind Controlled Trial
Our aim to study the efficacy of bupivacaine 0.25% with dexamethasone and that of bupivacaine
0.25% alone in transversus abdominis plane (TAP) block for postoperative analgesia in
patients undergoing an elective Caesarean section.
- Group 1: bupivacaine 0.25% + dexamethasone 8 mg
- Group 2: bupivacaine 0.25% A prospective Randomized Interventional double-blind study.
The pain and discomfort following cesarean delivery are mostly due to the abdominal wall
incision and dissection of muscles; it delays early ambulation and breastfeeding. This can
lead to postoperative complications such as thromboembolic disorders. So, providing an
effective and safe postoperative analgesic method seems to be mandatory. Opioid analgesia
remains the most effective means of relieving pain in a wide variety of conditions; however,
it may cause adverse effects such as nausea, vomiting, pruritus, urinary retention, and
respiratory depression. As the analgesia and the side effects of opioids are dose-dependent,
a multimodal approach may enhance analgesia, which in turn would decrease the side effects .
Mc Donnell and colleagues have reported that a transversus abdominis plane (TAP) block can
decrease the postoperative pain following abdominal surgery. The landmarks of this block were
first described in 2001 by Rafi. The TAP block has been performed for postoperative analgesic
control in patients undergoing radical prostatectomy, hysterectomy, cesarean delivery under
spinal anesthesia, and laparoscopic surgery.
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