Clinical Trials Logo

Clinical Trial Summary

This study compares the effect of two techniques of uterine closure, with or without endometrial suturing on isthmocele development after cesarean section.


Clinical Trial Description

Cesarean section is the most common surgery performed on pregnant women. Poor healing of the incision of the uterus leads to isthmocele development. Long-term morbidities associated with isthmocele are uterine scar pregnancy, uterine perforation, pelvic pain, and spotting-style bleeding after menstruation. Many factors that may affect the healing of uterine scar have been studied in the literature (i.e. Double or single-layer closure, locked or unlocked closure, uterine retroflection). Suturing complete fold of the wound lips during the closure of the uterus may cause the endometrial layer to be embedded in the myometrium and to form niche tissue. The study hypothesized that isthmocele development can be reduced by suturing without enclosing the endometrium during uterine closure. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04198324
Study type Interventional
Source Kocaeli University
Contact
Status Completed
Phase N/A
Start date December 16, 2019
Completion date December 14, 2020

See also
  Status Clinical Trial Phase
Completed NCT01890720 - Incisional Negative Pressure Wound Therapy for Prevention of Postoperative Infections Following Caesarean Section N/A
Completed NCT04076904 - Cesarean Niche Examination by Transvaginal us
Completed NCT05948150 - The Effect of Breastfeeding Pillow on Breastfeeding Self-Efficacy and Postpartum Comfort in Women Who Had Cesarean N/A
Completed NCT02369133 - Preemptive Analgesia With Intravenous Paracetamol for Post-cesarean Section Pain Control Phase 4
Completed NCT05770115 - A Randomized Clinical Study Based on Comparison Between Closure of Uterine Incision With Vicryl 2/0 Versus Vicryl 1 in Development of Uterine Niche. N/A
Completed NCT01891006 - Intervention for Postpartum Infections Following Caesarean Section N/A
Not yet recruiting NCT05206682 - Comparison of the Therapeutic Effects of Vaginal Repair With Leuprorelin and Vaginal Repair in the Treatment of Cesarean Section Scar Defect N/A
Completed NCT03498339 - The Effect of Cesarean Operative Technique on the Occurrence of Large Hysterotomy Scar Defects N/A
Recruiting NCT05590104 - Hysteroscopic Isthmocele Repair on IVF Outcome N/A
Completed NCT04046783 - Patch With Onion Extract and Allantoin for C-section Scar
Not yet recruiting NCT05363735 - Ultrasound Elastography Application in Cesarean Section Scar Defect
Recruiting NCT03936309 - A Comparison of Scar Infiltration, Scar Deactivation, and Standard of Care for the Treatment of Chronic, Post-Surgical Pain After Cesarean Section N/A
Recruiting NCT03140683 - Predictors of Scar Dehiscence in Patients With Previous Caesarean Section
Completed NCT03257514 - Effect of Alpha Lipoic Acid on Uterine Scar Healing After Cesarean Section Phase 2
Completed NCT03859258 - Ultrasound Based Study For Niche Development In The Uterine Cesarean Section Scar
Recruiting NCT03829774 - To Study and Evaluate the Effectiveness of Treatment by Percutaneous Electrical NeuroStimulation (PENS) for Post-operative Pain in Cesarean Section Patients Using Primary Relief v 2.0 N/A
Completed NCT06256822 - Technology-Based Breastfeeding Training After Cesarean
Completed NCT04070118 - Lower Uterine Segment Thickness and Term Pain,Previous Cesarean Section
Completed NCT03130387 - Prevalence of Cesarean Section Niche in Women With Unexplained Abnormal Uterine Bleeding N/A
Recruiting NCT03471858 - Mechanical Dilation of the Cervix in a Scarred Uterus N/A