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Cesarean Section Complications clinical trials

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NCT ID: NCT03505502 Completed - Clinical trials for Cesarean Section Complications

Reducing Blood Loss During Cesarean Myomectomy With Tranexamic Acid

TA
Start date: January 1, 2018
Phase: N/A
Study type: Interventional

This study was a double-blinded randomized controlled study conducted at Aswan University, Egypt from January 2018 to January 2020. Study inclusion criteria were women who attended the outpatient obstetric clinic, seeking antenatal care diagnosed with leiomyomas with pregnancy and with myoma staging from (3 to 6) according to FIGO staging. scheduled to undergo cesarean myomectomy (11) Exclusion criteria were: 1-Patients undergone vaginal delivery.2-Patients with a history of thromboembolic disease. 3-Cervical and broad ligament myoma. 4-Myoma FIGO staging

NCT ID: NCT03497325 Completed - Clinical trials for Cesarean Section Complications

Effect of Autologous Platelet-rich Plasma in Uterine Wound Healing

Start date: February 1, 2020
Phase: Phase 2
Study type: Interventional

The aim of this study is to evaluate the efficacy of intramuscular autologus platelet rich plasma on uterine wound healing after primary cesarean section

NCT ID: NCT03414762 Completed - Clinical trials for Cesarean Section Complications

PICO Negative Pressure Wound Therapy in Obese Women Undergoing Elective Cesarean Delivery.

Start date: April 1, 2019
Phase: Phase 3
Study type: Interventional

A randomized controlled, parallel group, superiority, open-label, single-institution, Phase 3 interventional clinical trial to evaluate clinical outcomes in obese gravidas undergoing elective cesarean delivery whose wounds were dressed with the PICO Negative Pressure Wound Therapy (NPWT) versus the standard dressing. We hypothesize that the PICO NPWT will reduce the incidence of surgical site occurrences and interventions and postoperative readmissions in obese women. The study will compare surgical site occurrences and surgical incision intervention incidence within 42 +/- 10 days post cesarean delivery in obese women who have the current standard-of-care dressing versus the PICO NPWT.

NCT ID: NCT03410199 Completed - Clinical trials for Cesarean Section Complications

Ultrasound Evaluation of Inferior Vena Cava Compression During Elective Cesarean Delivery.

Start date: January 29, 2018
Phase:
Study type: Observational [Patient Registry]

Aortocaval compression by the gravid uterus during the third trimester contributes to decreased venous return to the heart. Neuraxial anesthesia reinforces this hypotension by causing a vasodilatation and venous pooling of blood in the lower limbs. The current practice is to tilt the parturient 15 degrees on the operating table after neuraxial anesthesia in order to decrease this hypotension. Recent meta-analysis suggests there is no conclusive evidence to support the tilt position. The goal of our study is to compare ultrasound vena cava variation measurements in the supine versus the tilt position in third trimester parturients undergoing elective cesarean delivery.

NCT ID: NCT03404544 Completed - Clinical trials for Cesarean Section Complications

Impact of Carbetocin Administration on Heart Rate When Given as an Infusion Versus as a Bolus.

Start date: June 11, 2018
Phase: Phase 4
Study type: Interventional

Prospective, randomized and controlled study who will be conducted at Maisonneuve-Rosemont hospital with the following objectives: To determine if an infusion of carbetocin over 10 minutes will reduce hemodynamic side effects, especially the peak of heart rate, in comparison to a rapid intravenous bolus (less than 2 seconds). To determine if an infusion of carbetocin will reduce the other side effects of duratocin in comparison to a rapid intravenous bolus. Study plans to enroll 70 adult patients scheduled to undergo elective cesarean delivery under spinal anesthesia. Half of the patient will receive Carbetocin 100 mcg intravenous as a bolus (less than 2 seconds) and the other half will receive Carbetocin 100 mcg intravenous infusion over 10 minutes.

NCT ID: NCT03402685 Completed - Clinical trials for Cesarean Section Complications

Continuous Non-invasive Blood Pressure Measurement in C-section

ClearBirth
Start date: May 17, 2018
Phase: N/A
Study type: Interventional

The caesarean section is a frequently performed procedure in obstetrics and accounts for about 30% of all births in Germany. 55% to 68% of all caesarean sections are performed under spinal anesthesia. A possible side effect of spinal anesthesia is arterial hypotension with a prevalence of 70% to 80%. A placental hypoperfusion in the context of a reduced preload due to hypotension can reduce the fetal outcome. Early diagnosis and treatment of the hypotensive episode could reduce and at best prevent increased fetal morbidity. Due to their invasiveness due to the necessity of puncturing a distal artery of the extremity and the insertion of a catheter, established continuous blood pressure measurement procedures have disadvantages such as potential circulatory disorders of the hand, infections, bleeding and thrombosis and are therefore often not indicated in the context of an elective sectio. Non-invasive procedures such as NIBP, however, are discontinuous and may make a timely diagnosis of hypotension more difficult and delay therapy. The ClearSightTM system, which allows a continuous non-invasive blood pressure measurement, has been used in hip and knee joint surgery. There, a good correlation with invasive blood pressure measurements was found, particularly with regard to systolic and mean arterial pressure. An application in obstetrics has not yet been investigated. Due to the continuous measurement provided by ClearSightTM, continuous monitoring of blood pressure appears to be ensured, so that a faster reaction to previously undetected fluctuations in blood pressure can be expected compared to interval measurement.

NCT ID: NCT03396107 Completed - Clinical trials for Cesarean Section Complications

Antenatal Corticosteroid in Elective Cesarean Section

Start date: May 17, 2018
Phase: Phase 3
Study type: Interventional

Caesarean section is a risk factor for the development of neonatal respiratory complications, mostly respiratory distress syndrome (RDS) and transient tachypnoea of the new-born, both in term and preterm infants.

NCT ID: NCT03386240 Recruiting - Clinical trials for Surgical Site Infection

Antibacterial-coated Sutures at Time of Cesarean

ASTC
Start date: January 9, 2018
Phase: Phase 4
Study type: Interventional

Abdominal closure with antibacterial-coated sutures has been shown to reduce wound infections after a number of surgical procedures, but none of the previous trials included cesarean delivery. Our objective is to determine whether use of antibacterial-coated sutures reduces surgical site infection (SSI) after cesarean delivery.

NCT ID: NCT03377894 Not yet recruiting - Clinical trials for Cesarean Section Complications

Sharp Versus Blunt Uterine Incision Expansion

Start date: December 2017
Phase: Phase 2/Phase 3
Study type: Interventional

comparison between blunt versus sharp expansion of uterine incision at lower segment cesarean section in primigravida as regards the intra-operative blood loss & postoperative pain

NCT ID: NCT03355378 Recruiting - Clinical trials for Cesarean Section Complications

Short Versus Standard Post-operative Stay After Elective Cesarean Delivery

Start date: November 1, 2017
Phase: N/A
Study type: Interventional

After major open abdominal surgery, transient paralytic ileus usually follows. It has been suggested that stimulation of pain fibers, excessive sympathetic tone, and the release of inhibitory neurotransmitters from bowel wall associated with bowel manipulation and peritoneal irritation are responsible mechanisms. There have been concerns that early postoperative oral feeding would lead to vomiting with subsequent aspiration pneumonia, anastomotic leakage, and wound dehiscence.