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Cervicogenic Headache clinical trials

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NCT ID: NCT06100588 Recruiting - Clinical trials for Tension-Type Headache

The Classification and Treatment of Myofascial Headache: a Cross-sectional Study and Randomized Controlled Trial.

COMPHAS_RCT
Start date: December 6, 2023
Phase: N/A
Study type: Interventional

This project comprises two studies; a cross-sectional study and a randomized controlled trial. 1. The goal of the cross-sectional study is to compare multiple outcome parameters in different headache types: tension type (TTH), cervicogenic (CGH) and myofascial headache (MFH) as drafted by the International Classification of Headache Disorders (ICHD). Not only will these types be compared against each other, they will also be compared to healthy controls (HC). The main research questions are: - Are the criteria drafted by the International Classification of Headache Disorders (ICHD) discriminative for MFH? - Are there differences between the headache types (and healthy controls) in pain & disability scores, range of motion (ROM), muscle strength, muscle elasticity and hyperalgesia (=pain pressure treshold, PPT)? Participants will : - Fill out questionnaires about their pain and disability; - Be clinically investigated by a physiotherapist (anamnesis, inspection, examination of movement and structures of the neck and head); - Undergo a testing battery including neck ROM, neck muscle strength & elasticity and PPT measurement of the C2 processus spinosus, the bilateral upper trapezius muscle and the tibialis anterior muscle of the dominant leg. 2. The goal of this randomized controlled study is to investigate the additional effect of dry needling in the treatment of MFH patients, as compared to a treatment consisting of manual techniques only. The main question it aims to answer is: - Does manual therapy combined with dry needling provide an additional effect on pain, disability and functional outcomes in MFH patients, as compared to manual therapy alone? After the baseline test (see part 1), participants with MFH will be randomly divided to receive 4 sessions over 4 weeks of MT or MT + DN. Hereafter, the baseline test is repeated at 1 week and 3 months post-treatment.

NCT ID: NCT05972382 Recruiting - Clinical trials for Cervicogenic Headache

Associations Between Neck Muscle Fatigue, Joint Position Sense, and Headache in Cervicogenic Headache

Start date: July 28, 2023
Phase:
Study type: Observational

This research study aims to better understand the relationships between neck muscle function, neck joint position sense, and headache pain and disability in people with chronic cervicogenic headache. Cervicogenic headache is headache originating from the neck area. Participants will fill out questionnaires about their headache pain and ability to do daily activities. They will also do tests to measure neck muscle fatigue and neck joint position sense. Researchers will analyze if those with more neck muscle fatigue and poorer joint position sense have worse headache pain and disability. The results may improve understanding of cervical spine factors related to cervicogenic headache. This could help guide more targeted treatment approaches.

NCT ID: NCT05617365 Recruiting - Clinical trials for Cervicogenic Headache

Treating Chronic Cervicogenic Head and Neck Pain

CGH
Start date: September 1, 2022
Phase: Phase 1/Phase 2
Study type: Interventional

The primary aim is to test the combined effectiveness of OMT and targeted head exercise (THE) to achieve a significant decrease in headache measures of frequency, intensity, and duration in a Treatment group when compared to a Control group whose members receive only standard medical care. A parallel, 2-arm, longitudinal, randomized controlled trial (RCT) will focus upon female patients (18 to 75 years of age) who have been diagnosed with chronic cervicogenic headache (CeH) based upon a differential diagnosis that includes classification according to the International Headache Society Classification IHSD 3rd Edition, reproduction of referred headache resulting from manual pressure over the upper cervical regions, and objective MRI findings. It is estimated that a sample size of 30 will provide sufficient statistical power (79%) to detect an intervention effect that corresponds to a clinically meaningful recovery (60%). CeH is classified as a secondary headache disorder because the headache pain is a consequence of injury to, or disease of, the bony and/or soft tissues of the upper cervical spine. It has been reported that some patients diagnosed with CeH demonstrate atrophy and/or fatty infiltration (FI) of the RCPm muscles on MRI. FI and/or a reduction in the cross-sectional area (CSA) of active muscle would not be expected to be the direct cause of chronic headache, but either or both could prevent muscles from generating normal physiologic levels of force. It has been shown that there is a functional connection between the pain sensitive dura mater and RCPm muscles and it is known that mechanical stretching of the dura mater results in referred headache. While FI and/or a reduction in the CSA of active muscle would not be expected to be the direct cause of chronic headache, it is known that muscle pathology will result in functional deficits. It is proposed that pathology in RCPm muscles will compromise the normal functional relationship between the RCPm and the dura mater and result in referred head and neck pain. It is predicted that at the end of the study, the Treatment group will show a significant decrease in headache measures that will be accompanied by a significant increase in CSA and a significant decrease in FI on MRI, and restoration of a normal head posture that will not be seen in the Control group. The proposed study is unique in that we are proposing both a mechanism and a source for some instances of CeH. By testing the effectiveness of specific interventions to address a specific pathology within a specific headache population, and by restricting the study cohort to female subjects presenting with CeH, this study will increase the ability to detect a significant change in the outcomes by increasing the power of the statistical analysis.

NCT ID: NCT05582616 Recruiting - Clinical trials for Cervicogenic Headache

The Safety and Feasibility of tDCS Combined With Conservative Treatment for Cervicogenic Headaches

Start date: November 3, 2022
Phase: N/A
Study type: Interventional

Annually, up to 150,000 individuals are affected by cervicogenic headaches (CGH) in Canada with many of these cases being chronic. Current treatments for CGH are limited in efficacy and durability - indicating a dire need for novel interventions in this population. Transcranial direct current stimulation (tDCS) and physiotherapy have a high degree of safety and have been studied as interventions for many other chronic pain conditions and headache disorders. We propose to study the feasibility and safety of tDCS alongside physiotherapy for CGH further in a randomized sham controlled trial.

NCT ID: NCT05572489 Recruiting - Clinical trials for Cervicogenic Headache

Cervicogenic Headache, Cognitive Dysfunction

Start date: January 1, 2022
Phase:
Study type: Observational [Patient Registry]

The goal of this study was to determine the frequency of cognitive dysfunction in patients with cervicogenic headache. participants will be asked questions to determine their cognitive status at once.

NCT ID: NCT05500378 Recruiting - Clinical trials for Cervicogenic Headache

The Effects of a Specific Exercise Program on Subjects With Cervicogenic Headache

Start date: July 1, 2022
Phase: N/A
Study type: Interventional

This study explores with the use of MSK Ultrasound imaging if the obliquus capitis minor and the rectus capitis major can be contracted with specific exercises.

NCT ID: NCT05491915 Recruiting - Clinical trials for Cervicogenic Headache

The MONARCH Case Series Study: SPRINT® Peripheral Nerve Stimulation for the Treatment of Head Pain

Start date: October 24, 2022
Phase: N/A
Study type: Interventional

The purpose of this study is to learn if pain can be relieved by delivering small amounts of electricity (called "electrical stimulation") to the nerves at the top of the neck. This study will use a device called the SPRINT® PNS System. PNS stands for peripheral nerve stimulation (PNS). This device is cleared by the FDA for up to 60 days of use for relief of chronic or acute pain.

NCT ID: NCT05312645 Recruiting - Clinical trials for Cervicogenic Headache

Diclofenac Gel in the Treatment of Cervicogenic Headache

DITCH
Start date: June 2024
Phase: Phase 3
Study type: Interventional

The intervention will consist of the nursing staff applying 2 grams of diclofenac 1% gel topically to the posterior cervical region four times daily. The control group will receive petroleum jelly topically to the posterior cervical region four times daily. Patients will receive a pre-intervention and post-intervention survey incorporating the Numeric Assessment Scale and Headache Impact Test-6.

NCT ID: NCT05302479 Recruiting - Clinical trials for Cervicogenic Headache

Validating a Modified COMPASS 31questionnaire for Treatment Outcomes

COMPASS
Start date: April 15, 2022
Phase:
Study type: Observational

Eligible participants will complete the COMPASS 31 (year), modified COMPASS 31(one month) and the NSI (one month) questionnaires at baseline and complete the modified COMPASS 31 and the NSI after usual care of treatment. The investigators will 1. Compare results for the COMPASS 31(year) to the modified COMPASS 31(month) at baseline. 2. Compare modified COMPASS 31(month) to the NSI at baseline and post intervention.

NCT ID: NCT05240547 Recruiting - Clinical trials for Tension-Type Headache

Chiropractic Spinal Manipulation for Headache

Start date: February 14, 2022
Phase: N/A
Study type: Interventional

This is a pilot and feasibility randomized controlled trial to assess the efficacy of chiropractic spinal manipulative therapy in patients with tension-type and cervicogenic headache.