Immediate Treatment vs Colposcopic Follow-up for Biopsy-Proven CIN 1

Status Completed

Clinical Trial Summary

This study looks at immediate treatment of a cervix with CIN 1 versus regular six-month follow-up with colposcopy and treatment if CIN 1 progresses.

Clinical Trial Description

In women who present with biopsy-proven CIN 1, to compare the management approach of regular colposcopic follow-up and only treating progressive disease using the LEEP, with an approach of immediate treatment using LEEP. The primary outcome is progression to more advanced disease (i.e., CIN 2, CIN 3 or cancer). ;

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT00156026
Study type	Interventional
Source	Ontario Clinical Oncology Group (OCOG)
Contact
Status	Completed
Phase	Phase 3
Start date	November 2000
Completion date	September 2007

View Details

See also
Status	Clinical Trial	Phase
Active, not recruiting	`NCT04537156` - Efficacy, Immunogenicity and Safty Study of Recombinant Human Papillomavirus Vaccine(6,11,16,18,31,33,45,52,58 Type)(E.Coli)	Phase 3
Completed	`NCT02907333` - Testing Use of Condoms on Regression of Cervical Intraepithelial Neoplasia	N/A
Recruiting	`NCT02576262` - HPV Integration Testing for Human Papillomavirus-Positive Women	N/A
Completed	`NCT01029990` - Randomized Controlled Trial to Study Interventions to Increase Participation in Cervical Cancer Screening Program	Phase 0
Recruiting	`NCT05078528` - Low-cost Imaging Technology for Global Prevention of Cervical Cancer	N/A
Recruiting	`NCT05502367` - A Study of ABI-2280 Vaginal Tablet in Participants With Cervical Intraepithelial Neoplasia	Phase 1/Phase 2
Completed	`NCT02494310` - HRME: Screening for Cervical Cancer and Its Precursors in Low‐Resource Settings	N/A
Active, not recruiting	`NCT03429582` - Comparison of Cervical CIN II/III Treatment Outcomes With Thermal Ablation Device	N/A
Active, not recruiting	`NCT02140021` - Biospecimen Collection and Testing for the Prevalence of Anal Dysplasia and Anal Cancer in Patients With Cervical, Vaginal and Vulvar Dysplasia and Cancer	N/A
Not yet recruiting	`NCT05510830` - Diagnostic Cervical Conization for Persistent Infection or Integration of HPV	N/A
Completed	`NCT02237326` - Visual Inspection With Acetic Acid Compared to Lugol's Iodine in HIV-infected Women	N/A
Completed	`NCT00316706` - Human Papilloma Virus (HPV) Vaccine Trial in Young Adolescent Women With GlaxoSmithKline Biologicals' (GSK Bio) HPV-16/18 Vaccine	Phase 3
Withdrawn	`NCT03143491` - Study of SOR007 Ointment for Cervical Intraepithelial Neoplasia (CIN)	Phase 2
Completed	`NCT03293628` - Comparing Two Techniques of Haemostasis After Cervical Conization	Phase 2
Recruiting	`NCT05266898` - Immunogenicity of Gardasil-9 HPV Vaccine in People Living With HIV	Phase 4
Completed	`NCT02481414` - A Clinical Trial of PepCan to Two Therapy Arms for Treating Cervical High-Grade Squamous Intraepithelial Lesions	Phase 2
Completed	`NCT02247999` - Improving Cervical Cancer Screening Among HIV-Infected Women in India
Recruiting	`NCT04650711` - Immunohistochemical Staining of p16 for the Screening of Cervical Cancer	Phase 2
Recruiting	`NCT04646954` - DNA Methylation Testing for the Screening of Uterine Cervical Lesion	Phase 3
Completed	`NCT01544478` - V501 Safety and Efficacy Study in Japanese Women Aged 16 to 26 Years (V501-110)	Phase 4