Cervical Dystonia Clinical Trial
Official title:
Randomized Trial of a Specialized Physiotherapy Program Versus Standard Physiotherapy Advice in Patients With Cervical Dystonia (Spasmodic Torticollis).
The investigators wish to establish on a small scale the effectiveness of adding the
physiotherapy programme developed by Jean-Pierre Bleton to the present standard treatment
for cervical dystonia with a view to undertaking a larger UK-wide trial looking at overall
cost-effectiveness. Specifically, the investigators wish to establish:
1. Whether this specific physiotherapy program for cervical dystonia improves patient
outcomes in terms of neck position, pain, disability, and quality of life compared to
simple physiotherapy advice?
2. What is the minimal clinically important change in the new CDIP-58 quality of life
measure for cervical dystonia from a patient's perspective that could then be used to
plan a definitive trial of this technique?
3. What are the economic implications of the specialized physiotherapy programme?
n/a
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Outcomes Assessor), Primary Purpose: Treatment
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT03617367 -
Long-Term Safety and Efficacy of Repeat Treatments of DaxibotulinumtoxinA for Injection in Adults With Isolated Cervical Dystonia (ASPEN-OLS)
|
Phase 3 | |
| Not yet recruiting |
NCT04057911 -
A Trial of Non-invasive Stimulation in Cervical Dystonia
|
N/A | |
| Withdrawn |
NCT02180139 -
tDCS in Cervical Dystonia
|
N/A | |
| Completed |
NCT00541905 -
Daily Dystonia Practice - A Trial to Investigate NT 201, the Duration of Treatment Effect After One Injection Session and in Long-term Treatment in Cervical Dystonia
|
Phase 4 | |
| Unknown status |
NCT00418925 -
Efficacy of Dronabinol for the Treatment of Cervical Dystonia
|
Phase 2 | |
| Not yet recruiting |
NCT05715138 -
Comparison of Pallidal With Subthalamic Deep Brain Stimulation for Cervical Dystonia
|
N/A | |
| Completed |
NCT02131467 -
Safety and Tolerability of Perampanel in Cervical Dystonia
|
Phase 1/Phase 2 | |
| Completed |
NCT02959645 -
Assessment of Brain Activities in Cervical Dystonia
|
||
| Completed |
NCT03805152 -
Abobotulinum Toxin and Neubotulinum Toxin Injection in Cerivical Dystonia
|
Phase 3 | |
| Completed |
NCT04949594 -
Relief of Pain in Patients With Cervical Dystonia Through the Use of Transcutaneous Electric Nerve Stimulation (TENS)
|
||
| Recruiting |
NCT01664013 -
The Impact of Botulinum Toxin Treatment in Quality of Life of Cervical Dystonia Patients
|
Phase 4 | |
| Completed |
NCT00210431 -
Post Marketing Surveillance Study of Dysport
|
||
| Completed |
NCT00447772 -
Study to Assess the Efficacy and Safety of Dysport® in Cervical Dystonia
|
Phase 3 | |
| Completed |
NCT05157100 -
Clinical Study of Ingrezza (Valbenazine) for the Treatment of Cervical Dystonia
|
Phase 4 | |
| Completed |
NCT00257660 -
Randomized, Placebo-Controlled Study of AbobotulinumtoxinA (Dysport®) for the Treatment of Cervical Dystonia
|
Phase 3 | |
| Completed |
NCT05103202 -
Efficacy and Safety of 10-Week or Shorter vs 12-Week or Longer Injection Intervals of Botulinum Toxin
|
||
| Terminated |
NCT00760318 -
Keppra for Cervical Dystonia
|
Phase 2 | |
| Completed |
NCT00323765 -
Plasticity in Cervical Dystonia
|
N/A | |
| Completed |
NCT04171258 -
Clinical Trial to Compare the Safety and Efficacy of Botulax® Versus Botox® in Patients With Cervical Dystonia
|
Phase 1 | |
| Completed |
NCT04849988 -
A Phase 2 Study to Evaluate the Safety and Efficacy of ABP-450 in the Treatment of Cervical Dystonia
|
Phase 2 |