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NCT06433817 Clinical Trial

Spectral CT in Radiotherapy for Cervical Cancer

Cervical Cancer Clinical Trial

Official title:
The Clinical Research of Spectral CT in Radiotherapy for Cervical Cancer

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT06433817
Other study ID # SPRTCC-Trial
Secondary ID
Status Recruiting
Phase
First received
Last updated
Start date May 22, 2024
Est. completion date December 31, 2026

Study information
Verified date May 2024
Source Peking Union Medical College Hospital
Contact Fuquan Zhang, Porf
Phone 86 01069154072
Email zhangfq@pumch.cn
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

The purpose of this study was to explore the potential application of spectral CT for radiotherapy in cervical cancer.

Recruitment information / eligibility
Status Recruiting
Enrollment 150
Est. completion date December 31, 2026
Est. primary completion date May 22, 2026
Accepts healthy volunteers No
Gender Female
Age group 18 Years and older
Eligibility Inclusion Criteria: 1. All patients were confirmed cervical cancer by pathology 2. patients were treated with concurrent chemoradiotherapy 3. Spectral CT scans acquisition performed during the arterial phase and venous phase 4. All the patients underwent a 18F-FDG PET/CT before treatment Exclusion Criteria: 1. CT without spectral scans 2. History of allergy to intravenous contrast 3. Pregnant or potentially pregnant female subjects

Study Design

Related Conditions & MeSH terms

Intervention

Radiation:
• Spectral computed tomography scan
Spectral CT scans acquisition performed during the arterial phase and venous phase for cervical cancer

Locations
Country Name City State
China Peking Union Medical College Hospital Beijing Beijing

Sponsors (1)
Lead Sponsor Collaborator
Peking Union Medical College Hospital

Country where clinical trial is conducted

China, 

Outcome
Type Measure Description Time frame Safety issue
Primary Comparison of spectral CT derived data with response evaluation in cervical cancer To evaluate the tumor response of using quantitative parameters in spectral CT for cervical cancer patients according to RECIST 1.1 through study completion, an average of 2 year
Secondary Identifying metastatic lymph nodes in cervical cancer with spectral CT To evaluate the diagnostic performances of using spectral CT for identifying metastatic lymph nodes in patients with cervical cancer through study completion, an average of 2 year
Secondary Application of energy spectrum CT in brachytherapy of cervical cancer The ability to reduce metal artifact and assist in target delineation through study completion, an average of 2 year
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