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Clinical Trial Summary

The purpose of this study is to preliminarily explore the metastatic rate and clinical significance of the anterior leaf of vesicouterine ligament resection for early stage cervical cancer, so as to further improve the postoperative quality of life of patients and reduce the incidence of postoperative urinary complications.


Clinical Trial Description

The patients with cervical cancer who underwent abdominal radical hysterectomy(type C)plus pelvic lymph node dissection by the same surgical team at the Department of Gynecological Oncology, Sun Yat-sen Memorial Hospital, Sun Yat-Sen University, were included. According to the resection range of the anterior leaf of vesicouterine ligament (VUL), patients were divided into type C resection group (near the bladder wall) and B type resection group (above the ureter). The anterior leaf of the VUL in the type C resection group was sent to pathological biopsy separately, and the metastasis rate was further clarified by the pathological "ultrastaging" method. By comparing the clinicopathological characteristics of patients with metastasis and non-metastasis, the potential risk factors of VUL metastasis were analyzed. The oncological outcomes of patients with different resection range of the anterior VUL were compared. At the same time, the Functional Assessment of Cancer Therapy-Cervical(FACT-Cx)cervical cancer patient quality of life score table was used to evaluate cervical cancer patients after surgery. The relevant factors that may affect the quality of life score are included in the multiple linear regression analysis to obtain independent risk factors that affect the quality of life of the patient after surgery. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05904977
Study type Observational [Patient Registry]
Source Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Contact Huaiwu Lu
Phone 18688395806
Email luhuaiwu@mail.sysu.edu.cn
Status Recruiting
Phase
Start date April 1, 2019
Completion date December 31, 2024

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