Cervical Cancer Clinical Trial
— N6COfficial title:
Department of Radiation, Sun Yat-sen University
Evaluate the efficacy and safety of neoadjuvant chemotherapy (NAC) with albumin-bound paclitaxel and carboplatin followed by chemoradiation therapy (CRT) for stage IIIC cervical cancer patients with carcinoma >4 cm in greatest dimension and/or lymph node >2cm in short axis.
Status | Recruiting |
Enrollment | 280 |
Est. completion date | March 31, 2027 |
Est. primary completion date | March 31, 2024 |
Accepts healthy volunteers | No |
Gender | Female |
Age group | 18 Years to 70 Years |
Eligibility | Inclusion Criteria: 1. pathologically comfirmed : squamous cell, adenocarcinoma, or adenosquamous carcinoma of the uterine cervix; 2. FIGO (2018 International Federation of Gynecology and Obstetrics) stage IIIC with carcinoma >4 cm in greatest dimension and/or lymph node >2 cm in short axis at initial diagnosis. 3. age 18 to 70 years; 4. Eastern Cooperative Oncology Group performance status 0 to 2; 5. adequate organ function. Exclusion Criteria: 1. not at initial diagnosis; 2. with other kind of tumor. - |
Country | Name | City | State |
---|---|---|---|
China | Sun Yat-sen University Cancer Center | Guangzhou | Guangdone |
Lead Sponsor | Collaborator |
---|---|
Sun Yat-sen University |
China,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | 3-year progression-free survival ratio | the time from study randomization to 3 years, the ratio for patients without disease progression nor death. | up to 3 years |
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