A Study of DeTIL-0255 in Adults With Advanced Malignancies

Status Terminated

Clinical Trial Summary

This is a first-in-human Phase 1 multicenter, open-label oncology study designed to evaluate the safety and efficacy of NX-DeTIL-0255-201 in patients with advanced malignancies.

Clinical Trial Description

This study includes a safety run in and a cohort expansion. The safety run in will include patients with any of the indications under study including: Recurrent or persistent platinum-resistant epithelial ovarian cancer (EOC), including primary peritoneal and fallopian tube carcinoma Recurrent, metastatic, or persistent cervical carcinoma Advanced or recurrent endometrial cancer Cohort expansion will include patients with advanced malignancies who have received at least two prior systemic therapies in the same indications. ;

Study Design

Related Conditions & MeSH terms

Cervical Cancer
Endometrial Cancer
Endometrial Neoplasms
Platinum-resistant Ovarian Cancer

Clinical Trial Details

NCT number	NCT05107739
Study type	Interventional
Source	Nurix Therapeutics, Inc.
Contact
Status	Terminated
Phase	Phase 1
Start date	December 22, 2021
Completion date	May 9, 2023

View Details

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