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The Efficacy of Lymph Node Dissection for Stage IIICr of Cervical Cancer(CQGOG0103)

Cervical Cancer Clinical Trial

Official title:
Randomized Controlled Trial of the Efficacy of Lymph Node Dissection on Stage IIICr of Cervical Cancer

Clinical Trial Summary

This is an national, prospective, multicenter and randomized clinical study designed to determine if patients with stage IIICr of cervical cancer have longer PFS and/or OS with lymph node dissection before CCRT when compared to CCRT.

Clinical Trial Description

All eligible patients will be equally randomized between the 2 following treatment groups (stratified factors: whether para-aortic lymph nodes were image-positive): Standard treatment group: standard chemoradiation (Pelvic EBRT/Extended-field EBRT + concurrent platinum-containing chemotherapy+brachytherapy). Experimental group: open/minimally invasive pelvic and para-aortic lymph node dissection followed by chemoradiation. (Level of lymph node dissection: At least the inferior mesenteric artery. Chemoradiation will be performed postoperatively within 28 days.) ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04555226
Study type Interventional
Source Chongqing University Cancer Hospital
Contact Dongling Zou, M.D.
Phone 13657690699
Email cqzl_zdl@163.com
Status Recruiting
Phase N/A
Start date January 11, 2021
Completion date August 2029
View Details
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