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Clinical Trial Summary

The purpose of this study is to evaluate the safety and tolerability, pharmacokinetics, and pharmacodynamics of INCB099318 in select solid tumors.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms

  • Advanced Solid Tumors
  • Anal Carcinoma
  • Basal Cell Carcinoma (Unresectable or Metastatic)
  • Carcinoma
  • Carcinoma, Basal Cell
  • Carcinoma, Merkel Cell
  • Carcinoma, Renal Cell
  • Carcinoma, Squamous Cell
  • Cervical Cancer
  • Clear Cell Ovarian or Endometrial Carcinoma
  • Cutaneous Squamous Cell Carcinoma
  • Cyclin-dependent Kinase 12 Mutated Tumors
  • DNA Polymerase Epsilon Mutated Tumors (P286R and V411L)
  • Endometrial Neoplasms
  • Esophageal Squamous Cell Carcinoma
  • Merkel Cell Carcinoma
  • Mesothelioma
  • MSI-H/dMMR Tumors
  • Nasopharyngeal Carcinoma
  • Neoplasms
  • PD-L1 Amplified Tumor (9p24.1)
  • Sarcomatoid Renal Cell Carcinoma
  • Small Cell Lung Carcinoma
  • Small-cell Lung Cancer
  • Squamous Cell Penile Carcinoma
  • Urothelial Carcinoma, HCC

NCT number NCT04272034
Study type Interventional
Source Incyte Corporation
Contact
Status Active, not recruiting
Phase Phase 1
Start date March 26, 2021
Completion date June 20, 2026

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