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Clinical Trial Summary

This research is studying the level of oxygen in tumors during the brachytherapy procedure.


Clinical Trial Description

Tumors with low levels of oxygen have been found to be more resistant to standard radiation and chemotherapy treatments. For patients with tumors with low oxygen levels, it is not well known if higher radiation doses can overcome treatment resistance to radiation. Currently, there are limited ways of measuring tumor oxygen levels. The investigators believe that measuring tumor oxygen levels during the brachytherapy procedure will allow the investigators to develop better and improved oxygen measurement techniques, and ultimately improve clinical outcomes for patients, such as better local tumor control. This research study is a Pilot Study, meaning that this is the first time investigators are examining the oxygen sensor being used. This study is designed to test the oxygen sensor's ability to measure the oxygen levels within the participant's cervical tumor with the aid of magnetic resonance imaging (MRI) scans. MRI scans use magnets to make detailed images of the participant's tumor and the surrounding normal tissues during the brachytherapy procedure. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03970083
Study type Observational
Source Dana-Farber Cancer Institute
Contact
Status Active, not recruiting
Phase
Start date July 16, 2019
Completion date September 30, 2024

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