Cervical Cancer Clinical Trial
Official title:
A Research on Hidden Blood Loss in Open Radical Hysterectomy and Pelvic Lymphadenectomy
The aim of this cross-sectional study is to evaluate the hidden blood loss in patients who underwent open radical hysterectomy and identity its risk factors.
Status | Not yet recruiting |
Enrollment | 105 |
Est. completion date | September 1, 2022 |
Est. primary completion date | September 1, 2022 |
Accepts healthy volunteers | No |
Gender | Female |
Age group | 20 Years to 80 Years |
Eligibility | Inclusion Criteria: 1. Volunteer to participate in the study with informed consent; 2. Females aged 20-80 who are confirmed with cervical cancer and are treated with open radical hysterectomy and pelvic lymphadenectomy. Exclusion Criteria: 1. Pregnancy, lactation, postmenopause, or planned pregnancy within two years; 2. Suspected or identified as other tumors of genital tract; 3. History of hyperparathyroidism, infectious diseases (tuberculosis, AIDS), autoimmune diseases, or digestive system diseases (malabsorption, crohn disease and dysentery); 4. Other diseases or heavy injuries that will interfere with the results; 5. Simultaneous participation in another clinical study with investigational medicinal product(s) or researcher thinks the subjects are not suitable for this trial. |
Country | Name | City | State |
---|---|---|---|
China | TING LI | Wenzhou | Zhejiang |
Lead Sponsor | Collaborator |
---|---|
Second Affiliated Hospital of Wenzhou Medical University |
China,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | the volume of hidden blood loss (mL) | the volume of invisible blood loss occurring in patients who undergo open radical hysterectomy applying Gross's formula | 10 months after surgery | |
Secondary | the risk factors of hidden blood loss | Performing multiple linear regression analysis with SPSS 17.0, we plan to identify the factors which may increase the volume of hidden blood loss from possible factors like hypertension, diebetes, etc. | 10 months after surgery | |
Secondary | the volume of total blood loss (mL) | the vomule of patients' blood loss through the whole perioperative time according to the method of Nadler | 10 months after surgery | |
Secondary | the volume of visible blood loss (mL) | the visible blood loss including the blood in the suction bottle and in weighed compresses during the operation and the drainage volume after the operation | 10 months after surgery |
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