Internal Carotid Artery Blood Flow in Infants With Prone Position

Cerebral Lesion Clinical Trial

Official title:

A Study on Internal Carotid Artery Blood Flow Velocity Changes in Prone, Head Tilt and Trendelenberg Position in Infants: an Observational Study Using Transfontanel Ultrasound

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT05391282
• Other study ID #: 2204-162-1320
• Status: Not yet recruiting
• Start date: May 23, 2022
• Est. completion date: December 23, 2023

Study information

• Verified date: May 2022
• Source: Seoul National University Hospital
• Contact: Eun-hee Kim
• Phone: +82-2-2072-3664
• Email: beloveun[@]snu.ac.kr
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Little is known about how implementation of prone position contributes to general anesthesia-induced decrease in cerebral blood flow in infants. The investigators investigated this question in participants undergoing untethering, hypothesizing that cardiorespiratory changes during this procedure would reduce cerebral perfusion.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 20
• Est. completion date: December 23, 2023
• Est. primary completion date: December 23, 2023
• Accepts healthy volunteers: No
• Gender: All
• Age group: N/A to 15 Months

Eligibility

Inclusion Criteria:

• pediatric neurosurgical patients receiving surgery under prone position

Exclusion Criteria:

• patients diagnosed as hydrocephalus
• premature closure of fontanelle
• patients diagnosed as patent ductus arteriosus or other congenital heart disease.

Related Conditions & MeSH terms

• Cerebral Lesion

Intervention

Other:
• ultrasound assessment
Transfontanel ultrasound assessment before and after prone positioning

Locations

Country	Name	City	State
Korea, Republic of	Seoul national university hospital	Seoul

Sponsors (1)

Lead Sponsor	Collaborator
Seoul National University Hospital

Country where clinical trial is conducted

Korea, Republic of, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Changes of internal carotid artery blood flow velocity		from induction of anesthesia to end of operation, about 3 hours