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Brain Oxygenation-II — BOx-II  

Cerebral Hypoxia Clinical Trial

Official title:
Brain Oxygenation in Extremely Preterm Infants-II

Clinical Trial Summary

The Brain Oxygenation-II study (BOx-II) is a phase-II, multicenter, single-arm clinical trial evaluating interventions based on near-infrared spectroscopy (NIRS) monitoring of cerebral oxygen saturation in extremely premature infants. Enrolled infants will follow a treatment guideline to maintain cerebral oxygen saturation in a target range within the first 72 hours of life. The primary outcomes will include interventions used to maintain cerebral saturation in target range, rates of cerebral hypoxia and systemic hypoxia, and a composite of death or severe brain injury detected on term-equivalent magnetic resonance imaging.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05171881
Study type Interventional
Source Stanford University
Contact
Status Active, not recruiting
Phase Phase 2
Start date April 7, 2022
Completion date April 2025
View Details
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