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Cerebral Haemodynamics clinical trials

View clinical trials related to Cerebral Haemodynamics.

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NCT ID: NCT03983694 Completed - Clinical trials for Erythrocyte Transfusion

Cerebral Haemodynamic Changes by Red Blood Cell Transfusion in Neonates

Start date: June 20, 2019
Phase:
Study type: Observational

The timing and the indications for red blood cell (RBC) transfusions remain one of the most controversial topic in Neonatology. Indeed, biomarkers routinely used to discriminate between patients that will benefit from RBC transfusion appear insufficient. Tissue oxygenation could be useful to determine the need for transfusion. This study aims to assess the effects of RBC transfusion on cerebral haemodynamics and oxygenation in neonates with a new hybrid optical device (BabyLux) integrating time-resolved spectroscopy (NIRS-TRS) and diffuse correlation spectroscopy (DCS). It is hypothesized that cerebral blood flow decreases after RBC transfusion, whereas cerebral oxygenation and oxygen metabolism are unchanged.

NCT ID: NCT01376882 Completed - Cognitive Function Clinical Trials

Cognitive and Cerebral Blood Flow Effects of 2-week Caffeine Abstinence or Maintenance

Start date: March 2011
Phase: N/A
Study type: Interventional

The purpose of this study is to determine the effects of 2 weeks caffeine abstinence as compared to 2 weeks caffeine maintenance (300mg per day)on cognition and mood. Cerebral blood flow effects will also be assessed in a subset of participants. The role of caffeine abstinence/maintenance in the acute effects of caffeine will also be explored.