Central Venous Pressure Clinical Trial
Official title:
Clinical Validation of a Non-Invasive Central Venous Pressure Device in Comparison With Physical Examination in Patients With Chronic Kidney Disease and Healthy Volunteers
The primary objective of this study is to determine whether a correlation exists between the Mespere Non-Invasive Central Venous Pressure (NICVP) device for measuring central venous pressure (CVP), and assessment of CVP via physical examination.
The estimation of central venous pressure (CVP) is part of routine clinical examination.
Central venous pressure is the indication of the pressure in the right atrium of the heart
and it can be measured by determining the height of the blood column in the internal or
external jugular vein. Clinical use of CVP has a wide range of applications including
diagnosis of heart failure, pleural effusion, hypervolemia, hypovolemia, and sepsis. The
standard clinical method for attaining CVP non-invasively is the physical examination of
jugular venous pulse (JVP). The JVP provides a useful estimate of the CVP.
It is often difficult to identify the internal jugular vein to determine the JVP. The
internal jugular vein is deep and adjacent to the carotid artery and pulsations derived from
the artery may obscure the subtle venous pulsations. Manoeuvres to differentiate carotid
pulsation and jugular pulsation are helpful in identifying the internal jugular vein,
however determining the JVP based on the internal jugular vein examination is difficult.
Examination of the external jugular vein to determine JVP is an appealing alternative. The
external jugular vein is easier to visualize and studies have demonstrated that this is a
reliable method that correlates highly with catheter measured CVP.
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Observational Model: Cohort, Time Perspective: Prospective
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| Completed |
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