Central Venous Pressure (CVP) Assessment by Ultrasound and Physical Examination

Central Venous Pressure Clinical Trial

Official title:

Use of Ultrasound to Determine Central Venous Pressure in Critically Ill Patients

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01099241
• Other study ID #: 20076777
• Status: Completed
• Phase: N/A
• First received: March 26, 2010
• Last updated: April 5, 2010
• Start date: August 2007
• Est. completion date: March 2010

Study information

• Verified date: March 2010
• Source: University of Iowa
• Contact: n/a
• Is FDA regulated: No
• Health authority: United States: Institutional Review Board
• Study type: Observational

Clinical Trial Summary

Ultrasound may be useful for noninvasively determining the central venous pressure. We intend to compare the clinical examination of the neck veins; ultrasound delineation of the internal jugular vein; and the central venous pressure measured with an intravascular catheter.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 38
• Est. completion date: March 2010
• Est. primary completion date: March 2010
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• adult medical or surgical ICU patients who have preexisting central venous (jugular/subclavian only) catheters.

Exclusion Criteria:

• subjects with only a femoral venous catheter.

• subjects whose CVP measurement by the indwelling catheter exceeds 20cm of water.

• subjects younger than 18 years old.

• inability to obtain informed consent from the subject or the subjects authorized representative.

Study Design

Time Perspective: Prospective

Related Conditions & MeSH terms

• Central Venous Pressure

Locations

Country	Name	City	State
United States	University of Iowa	Iowa City	Iowa

Sponsors (1)

Lead Sponsor	Collaborator
University of Iowa

Country where clinical trial is conducted

United States, 

References & Publications (8)

Baumann UA, Marquis C, Stoupis C, Willenberg TA, Takala J, Jakob SM. Estimation of central venous pressure by ultrasound. Resuscitation. 2005 Feb;64(2):193-9. — View Citation

Bazaral M, Harlan S. Ultrasonographic anatomy of the internal jugular vein relevant to percutaneous cannulation. Crit Care Med. 1981 Apr;9(4):307-10. — View Citation

Cook DJ. Clinical assessment of central venous pressure in the critically ill. Am J Med Sci. 1990 Mar;299(3):175-8. — View Citation

Davison R, Cannon R. Estimation of central venous pressure by examination of jugular veins. Am Heart J. 1974 Mar;87(3):279-82. — View Citation

Lipton B. Estimation of central venous pressure by ultrasound of the internal jugular vein. Am J Emerg Med. 2000 Jul;18(4):432-4. — View Citation

Lipton BM. Determination of elevated jugular venous pressure by real-time ultrasound. Ann Emerg Med. 1999 Jul;34(1):115. — View Citation

Rizvi K, Deboisblanc BP, Truwit JD, Dhillon G, Arroliga A, Fuchs BD, Guntupalli KK, Hite D, Hayden D; NIH/NHLBI ARDS Clinical Trials Network. Effect of airway pressure display on interobserver agreement in the assessment of vascular pressures in patients with acute lung injury and acute respiratory distress syndrome. Crit Care Med. 2005 Jan;33(1):98-103; discussion 243-4. — View Citation

Vinayak AG, Levitt J, Gehlbach B, Pohlman AS, Hall JB, Kress JP. Usefulness of the external jugular vein examination in detecting abnormal central venous pressure in critically ill patients. Arch Intern Med. 2006 Oct 23;166(19):2132-7. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Correlation of CVP measurement via ultrasound and central venous catheter	CVP as determined non-invasively with the transcutaneous ultrasound probe will correlate with a high degree of accuracy to the measurement obtained invasively by the catheter and pressure transducer.	At data collection: this is a physiologic study	No
Secondary	Correlation of CVP measurement via physical examination of IJV and EJV.	Despite its more tortuous course and smaller caliber, the external jugular vein will be as reliable (compared to the catheter) as the internal jugular to estimate CVP	At data collection: physiologic study	No