Clinical Trials Logo
  1. Home
  2. Central Sensitisation
  3. NCT05022251

Identifying Pain Generators and Potentiators of Residual Complaints Following Lumbar Discectomy — DISC-PAIN  

Lumbar Radiculopathy Clinical Trial

Official title:
Identifying Pain Generators and Potentiators of Residual Complaints Following Lumbar Discectomy

Clinical Trial Summary

Lumbar discectomy (i.e. surgically removing a hernia) is frequently performed in Belgium to treat lumbar radiculopathy. Every year >12,000 interventions are performed with variable long-term results. The treatment success of this procedure varies and up to 41% of the patients report post-operative persistent pain complaints, and consequently suffer from failed back surgery syndrome (FBSS). Chronic complaints in FBSS following lumbar discectomy are usually treated with symptomatic interventions (including painkillers, neuromodulation, etc), rather than from a biopsychosocial perspective. In order to develop a focused and effective treatment strategy, it is crucial to first gain insight into how persons with persistent complaints after lumbar discectomy differ from those without persistent symptoms. Different known contributing factors entail type of surgery, muscle and psychosocial impairments. Although in scientific and clinical literature it is assumed that dysfunctional pain processing also plays an important mechanistic role in FBSS, there is a lack of research to support this. However, this knowledge is crucial to depict the full mechanistic picture of pain generators and potentiators in FBSS. Therefore, we will examine whether residual complaints persisting following lumbar discectomy can be accounted for by underlying dysfunctional pain processing and whether a clinical classification algorithm can be used to identify the predominant pain mechanism in these patients.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05022251
Study type Observational
Source University Ghent
Contact
Status Terminated
Phase
Start date October 1, 2021
Completion date October 31, 2023
View Details
See also
  Status Clinical Trial Phase
Terminated NCT05047679 - The Effectiveness of Pain Neuroscience Education in At-risk Patients Following Surgery for Lumbar Radiculopathy N/A
Withdrawn NCT03543033 - Preoperative Corticosteroid Epidural Injection and Lumbar Decompression Surgery Outcomes N/A
Recruiting NCT06076408 - Effects of SNAGS With and Without Pilates in Lumbar Disc Bulge Patients N/A
Completed NCT03133845 - Shaping Anesthetic Techniques to Reduce Post-operative Delirium N/A
Completed NCT06087107 - Comparative Effects Of High Intensity Spinal Decompression Exercises And Eldoa In Patients Of Lumbar Radiculopathy N/A
Completed NCT04852900 - Different Dosage of Decompression Therapy on Symptoms of Lumbar Radiculopathy N/A
Recruiting NCT04212949 - The Effect of Transcranial Magnetic Stimulation Therapy in Patients With Lumbar Radiculopathy N/A
Terminated NCT03952377 - Safety and Efficacy of SX600 Administered by Lumbosacral Transforaminal Epidural Injection for Radicular Pain Phase 1/Phase 2
Recruiting NCT06339931 - Lumber Spine Mobilization and Spinal Traction on Lumber Radiculopathy. N/A
Recruiting NCT04540068 - Prediction of TEI Success in Sciatica
Recruiting NCT05953727 - Low Level LASER Therapy With and Without Proprioceptive Stimulation Among Discogenic Lumbar Radiculopathy Patients N/A
Recruiting NCT05922228 - Effects of Neural Flossing and PNF on Lumbar Radiculopathy N/A
Completed NCT05449288 - Urdu Version Of Modified Oswestry Low Back Pain Scale; A Reliability And Validity Study
Completed NCT05874427 - Comparison Between the Imaging Consent Form and the Existing Narrative Consent Form N/A
Terminated NCT01443819 - Lumbar Transforaminal Epidural Corticosteroid Injection(s) Versus Defined Physical Therapy Phase 3
Recruiting NCT05535010 - The Effect of the Presence of Active Trigger Points in the Muscles Innervated by the Affected Nerve Roots on the Treatment Results of Transforaminal Epidural Steroid Injection in Patients With Lumbar Radiculopathy. N/A
Recruiting NCT06154005 - OsteoAdapt SP Advanced Bone Graft Feasibility Study - Transforaminal Interbody Lumbar Fusion Phase 1/Phase 2
Completed NCT04674917 - Effects of Decompression in Patient With Acute vs Chronic Lumbar Radiculopathy N/A
Not yet recruiting NCT06296303 - Effect of Pulsed Magnetic Therapy Versus Phonophoresis in Discogenic Lumbar Radiculopathy Patients N/A
Completed NCT04887285 - Virtual Reality as a Substitute for Procedural Sedation During Epidural Steroid Injections N/A