Central Precocious Puberty Clinical Trial
Official title:
Multi-site Study of Comprehensive Treatment for Children Precocious Puberty
This is a prospective, multicentric, comparative, non-randomized interventional study in which subjects diagnosed with central precocious puberty (CPP) and early puberty (EP) were treated for 6 months to compare the effect with GnRHa and traditional Chinese medicines.
740 girls with CPP and EP participated in this study, all participates were divided into GnRHa group, traditional chinese medicines group and blank group. After at least six months therapy with GnRHa or traditional Chinese medicines, the investigators compare clinical parameters, sex hormone, bone age and ovarian ultrasound in three groups. ;
Allocation: Non-Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT00779103 -
Histrelin Subcutaneous Implant in Children With Central Precocious Puberty
|
Phase 3 | |
| Not yet recruiting |
NCT05341128 -
A Study of Medical Records From Children With Central Precocious Puberty (CPP) in China
|
||
| Completed |
NCT04736602 -
Efficacy and Safety Study of Triptorelin 3-Month Formulation in Chinese Children With Central Precocious Puberty.
|
Phase 3 | |
| Recruiting |
NCT05341115 -
A Study of Leuprolide Acetate Depot in Children With Central Precocious Puberty
|
Phase 4 | |
| Completed |
NCT02993926 -
A Study to Assess the Safety and Efficacy of Enantone (Leuprorelin) in Central Precocious Puberty (CPP) Among Chinese Participants
|
||
| Recruiting |
NCT02811471 -
Pharmacokinetic Study of Leuprolide Acetate Injectable Suspension in the Treatment of Central Precocious Puberty
|
Phase 3 | |
| Completed |
NCT03316482 -
Leuprorelin Acetate DPS (Leuplin DPS) Treatment Quarterly in Patients With Central Precocious Puberty
|
Phase 4 | |
| Recruiting |
NCT06129539 -
A Study to Assess the Efficacy, Safety and Pharmacokinetics of Debio 4326 in Pediatric Participants Receiving Gonadotropin-Releasing Hormone Agonist Therapy for Central Precocious Puberty
|
Phase 3 | |
| Completed |
NCT01634321 -
The Clinical Trial to Evaluate the Efficacy and Safety of Luphere Depot Inj. 3.75mg(Leuprolide Acetate 3.75mg) in Patients With Precocious Puberty
|
Phase 4 | |
| Terminated |
NCT02006680 -
Markers of Pubertal Suppression During Therapy for Precocious Puberty
|
||
| Completed |
NCT01278290 -
Comparative Validation of the Triptorelin Test for the Diagnosis of CPP in Girls
|
Phase 3 | |
| Completed |
NCT02427958 -
A Study to Assess the Safety and Efficacy of Leuprorelin in Central Precocious Puberty in Chinese Participants
|
Phase 4 | |
| Completed |
NCT05029622 -
A Study to Assess the Efficacy and Safety of the Triptorelin 6-month Formulation in Paediatric Participants With Central Precocious Puberty.
|
Phase 3 | |
| Recruiting |
NCT06025409 -
Evaluate the Efficacy and Safety of DWJ108J
|
Phase 3 | |
| Completed |
NCT01467882 -
Efficacy, Safety, and Pharmacokinetics (PK) of Triptorelin 6-month Formulation in Patients With Central Precocious Puberty
|
Phase 3 | |
| Recruiting |
NCT00438217 -
Analysis of Genetic and Environmental Parameters Influencing Growth Rate of Precocious Puberty Children
|
Phase 4 |