Central Nervous System Lymphoma Clinical Trial
Official title:
Identification of Genes Involved in the Pathogenesis of Gliomas by Transcriptome Analysis
RATIONALE: Studying the genes expressed in samples of tissue from patients with cancer in
the laboratory may help doctors learn more about changes that occur in DNA and identify
biomarkers related to cancer. It may also help doctors predict how patients will respond to
treatment.
PURPOSE: This research study is looking at tissue samples from patients with glioma or other
brain tumors.
OBJECTIVES:
Primary
- To better understand the pathophysiology of gliomas and identify molecular markers that
may predict prognosis and progression or that could identify new therapeutic
approaches.
Secondary
- To compare gene expression profiles, in terms of response to treatment, and attempt to
isolate subgroups of patients with objective response to certain types of chemotherapy
or radiotherapy.
OUTLINE: This is a multicenter study.
Biological samples are collected from patients at time of surgery for diagnostic and/or
treatment purposes.
;
Observational Model: Cohort, Time Perspective: Retrospective
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