Incidence and Risk Factors of Central Line Catheter Related Thrombosis

Central Line Complication Clinical Trial

Official title:

Study About the Incidence and Risk Factors of the Central Line Catheter Related Right Internal Jugular Vein Thrombosis in Pediatric Patients

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03450785
• Other study ID #: 1801-152-922
• Status: Completed
• Start date: March 7, 2018
• Est. completion date: April 8, 2020

Study information

• Verified date: March 2021
• Source: Seoul National University Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Central venous catheters are frequently used for monitoring haemodynamic status and rapidly delivering fluid therapy during the peri- and postoperative periods. Indwelling central venous catheters are typically used 7-14 days postoperatively for additional monitoring and treatment, but patients may develop asymptomatic catheter-related thrombosis, leading to life-threatening pulmonary embolism and death. Early detection helps to avoid such complications. This prospective observational study investigated the risk factors associated with catheter-related right internal jugular vein thrombosis in pediatric patients. The study enrolled 80 pediatric patients who were scheduled to receive central venous catheter. To detect thrombus formation, Doppler ultrasound examinations from the thyroid cartilage level to the supraclavicular region were used after CVC placement and on each of the following days until the catheter was removed.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 80
• Est. completion date: April 8, 2020
• Est. primary completion date: April 8, 2020
• Accepts healthy volunteers: No
• Gender: All
• Age group: N/A to 6 Years

Eligibility

Inclusion Criteria:

• pediatric patients who were scheduled to catheterize central venous catheter

Exclusion Criteria:

• patients who had skin infections on the right side of the neck, making them unsuitable for placement of the catheter via the right side of the neck
• patients who had blood coagulation lesions or bleeding tendencies
• patients with thrombocytopenia
• patients with a history of right internal jugular vein thrombosis
• patients who presented right internal jugular vein thrombosis or stenosis on preoperative Doppler ultrasound examination

Related Conditions & MeSH terms

• Central Line Complication
• Thrombosis

Intervention

Other:
• ultrasound examination
Doppler ultrasound examinations from the thyroid cartilage level to the supraclavicular region were used after CVC placement and on each of the following days until the catheter was removed.

Locations

Country	Name	City	State
Korea, Republic of	Jin-Tae Kim	Seoul

Sponsors (1)

Lead Sponsor	Collaborator
Seoul National University Hospital

Country where clinical trial is conducted

Korea, Republic of, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	thrombus formation using doppler ultrasound examination of internal jugular vein		after central venous catheter placement and on each of the following days until the catheter was removed (maximum 5 days)