Central Aortic Pressure Clinical Trial
Official title:
Impact of Nebivolol on Central Aortic Pressure
| Verified date | July 2011 |
| Source | Creighton University |
| Contact | n/a |
| Is FDA regulated | No |
| Health authority | United States: Institutional Review Board |
| Study type | Interventional |
A randomized, cross-over, single-blind study to compare the effects of nebivolol and metoprolol on central aortic pressure and peripheral brachial pressure in patients with stable cardiovascular disease.
| Status | Withdrawn |
| Enrollment | 0 |
| Est. completion date | May 2010 |
| Est. primary completion date | May 2010 |
| Accepts healthy volunteers | No |
| Gender | Both |
| Age group | 45 Years to 75 Years |
| Eligibility |
Inclusion Criteria: - Subjects with history of hypertension - Subjects who have received metoprolol for a minimum of 3 months Exclusion Criteria: - Patients who have had an acute myocardial infarction, coronary revascularization or who have been hospitalized for heart failure or cardiac arrhythmia in the past 6 months |
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Crossover Assignment, Masking: Single Blind (Investigator), Primary Purpose: Treatment
| Country | Name | City | State |
|---|---|---|---|
| United States | The Cardiac Center at Creighton University | Omaha | Nebraska |
| Lead Sponsor | Collaborator |
|---|---|
| Creighton University |
United States,
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | Stable blood pressure | Subjects will be randomized to nebivolol or metoprolol. Their medication will be titrated so that their blood pressure is within 10% of their initial reading. | 6 months | No |