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Cellulite clinical trials

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NCT ID: NCT05624216 Completed - Cellulitis Clinical Trials

Radiofrequency and Targeted Pressure Energy for Cellulite Reduction

Start date: July 30, 2019
Phase: N/A
Study type: Interventional

This study will evaluate the clinical efficacy and safety of radiofrequency heating and targeted pressure energy for reduction in the appearance or cellulite. The study is a prospective multi-center open-label single-arm study. Subjects will be required to complete four (4) treatment visits and two to three follow-up visits - 1, 3 and 6 months after the last therapy visit. All of the study subjects will receive the treatment with the subject device.

NCT ID: NCT05441917 Suspended - Cellulite Clinical Trials

Phototherapy and Radiofrecuency for Cellulite

Start date: September 1, 2023
Phase: N/A
Study type: Interventional

Cellulite is a condition that consists of an edematous infiltration of connective tissue. It has multiple factors in its etiology, making it difficult to choose just one type of treatment. Thus, aiming at greater therapeutic efficiency, the association of therapies is studied. This research aims to evaluate the Sanae method for the treatment of cellulite. The sample will feature 60 participants who have different degrees of cellulite. Initially, a pilot study will be carried out with 12 patients, divided into two groups: G1-P: 6 volunteers with grade 3 cellulite and G2-P: 6 volunteers with grade 2 cellulite. At the end of this step, the sample for the new step will include 48 people from female, who also have the same characteristics as the previous groups. Again they will be divided equally into two groups: G1: 24 volunteers with grade 3 cellulite and G2: 24 volunteers with grade 2 cellulite. Assessment protocols, photographs, ultrasound, magnetic resonance imaging and questionnaires will be used. The treatment will take place 3 times a week for 50 minutes, and will consist of a combination of therapies such as Carboxitherapy using equipment from the Ibramed™ brand, model Aires™, phototherapy from the Ibramed™ brand, model Antares™, radiofrequency from the Ibramed® brand, the Neartek™ model and manual therapy, in addition, the volunteers will wear compressive shorts during treatment. A total of 15 sessions will be carried out and the reassessment will be carried out after the last session, with the repetition of all the exams mentioned and photos for analysis of the results.

NCT ID: NCT05419505 Completed - Cellulite Clinical Trials

Study of Different Interventions to Reduce Bruising Following CCH-Aaes Treatment for Cellulite of the Buttocks

APHRODITE
Start date: June 15, 2022
Phase: Phase 2
Study type: Interventional

The study will evaluate the effect of different doses, strengths (concentrations), diluent additives, depths of injection, and methods of injection on the severity of bruising potentially induced by QWO (collagenase clostridium histolyticum-aaes [CCH-aaes]).

NCT ID: NCT05405062 Not yet recruiting - Clinical trials for Efficacy of Treatment of Cellulite Using Carboxy Therapy

Carboxytherapy Versus Short-pulsed Nd Yag Laser in Cellulite

Start date: June 1, 2022
Phase: N/A
Study type: Interventional

To evaluate the efficacy of carboxytherapy versus short-pulsed 1064 nm Nd-YAG laser combined with subcision in treatment of cellulite using clinical assessment and ultrasound imaging.

NCT ID: NCT05358847 Completed - Cellulite Clinical Trials

Treatment for Cellulite Appearance

Start date: November 21, 2021
Phase: N/A
Study type: Interventional

Open-label, non-randomized, prospective, multi-center, self-controlled clinical study with masked evaluation.

NCT ID: NCT05309525 Completed - Cellulite Clinical Trials

Effect of Oral TXA on Buttock Bruising Post CCH Injections in Adult Females

Start date: April 22, 2022
Phase: Phase 4
Study type: Interventional

This is an open-label, randomized, multiple dose IIR study to evaluate the effect of Lysteda™ on bruising following QWO™ injections to the buttocks in female subjects presenting with moderate to severe cellulite. Following determination of eligibility based on inclusion/exclusion assessment, the subjects will be randomized to either Cohort A, Cohort B, or Cohort C, based on order of enrollment. Each Cohort will receive 3 Qwo™ treatments spaced 21 days apart, with 1300 mg of Lysteda™ TID PO at one, two, or all three treatments of Qwo™. Cohort A will be given tranexamic acid at the first treatment, Cohort B at the first and second treatment, and Cohort C at all three treatments. All buttock CCH injections will follow the on-label injection protocol. Subjects will participate in the study for 65 days total, with an additional screening period of 14 days. There will be a total of 11 visits (Screening, Day 1, Day 4, Day 14, Day 22, Day 26, Day 36, Day 43, Day 47, Day 57, Day 65).

NCT ID: NCT05249257 Completed - Cellulite Clinical Trials

Durability and Safety of CCH With Two Different Injection Techniques in Cellulite With Laxity

Start date: January 25, 2022
Phase:
Study type: Observational

All participants who completed the EN3835-224 study will be invited to participate in this observational study to evaluate long term durability of response and safety.

NCT ID: NCT05199506 Completed - Cellulite Clinical Trials

Study to Evaluate the Safety and Effectiveness of the RAP Device for the Improvement in the Appearance of Cellulite

Start date: May 4, 2021
Phase: N/A
Study type: Interventional

The purpose of this single site clinical study is to evaluate the safety and effectiveness of the Soliton Rapid Acoustic Pulse (RAP) device for the improvement of cellulite comparing two different RAP treatment doses.

NCT ID: NCT05064761 Completed - Cellulite Clinical Trials

Safety and Effectiveness of Poly-l-lactic Acid (PLLA) for the Improvement in Appearance of Cellulite

Start date: November 19, 2021
Phase: N/A
Study type: Interventional

This pilot study has been designed to evaluate the safety and effectiveness of PLLA as a single regimen for the improvement in appearance of cellulite after changes in reconstitution procedure.

NCT ID: NCT05026216 Completed - Cellulite Clinical Trials

To Assess the Effectiveness of Multiple Dose, Multiple Concentrations of Qwo, for the Treatment of Mild to Moderate Cellulite.

Start date: March 29, 2021
Phase: Phase 4
Study type: Interventional

This is a single center, off-label, multiple dose, multiple injection areas, Phase 4 study to assess the safety and efficacy of multi-dilution CCH in adult women with mild or moderate edematous fibrosclerotic panniculopathy (EFP). 5 subjects will be screened and dosed in the buttock and thigh areas using a multi-dilution injection technique. Qualified subjects (determined by investigator assessment) will receive a single vial of 0.84 mg of CCH to treatment areas (buttocks and thighs) for a total dose of 1.68 mg in both buttocks and both thighs per treatment session × 3 treatment sessions (Day 1, Day 22, and Day 43). Subjects will have follow-up visits at approximately 90 after Day 1.