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Clinical Trial Summary

Fluoride is very effective in preventing dental decay (cavities) when applied in the form of a varnish on tooth surfaces. The purpose of this study is to verify if fluoride-releasing primer (OpalSeal) offers more protection against early dental decay (cavity) compared to conventional primer (Transbond XT) during treatment with braces.


Clinical Trial Description

Primers are a type of 'glue' routinely used in orthodontics to attach brackets (metallic components) to the teeth. OpalSeal is a fluoride-releasing primer that has the potential to reduce cavities in patients receiving braces.

Orthodontic patients are at particular risk of developing two types of early carious lesions (decay):

1. Around the brackets called White Spot Lesions and

2. Along the sides of the teeth after slenderization procedure called inter-proximal reduction (IPR).

Our research questions are:

1. Can OpalSeal offer protection against white spot lesions (WSL) around the brackets?

2. Can OpalSeal offer protection against decay on the sides of teeth following IPR? ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03722264
Study type Interventional
Source Virginia Commonwealth University
Contact
Status Completed
Phase N/A
Start date November 16, 2017
Completion date April 12, 2019

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