Efficacy of Etoricoxib on Peripheral Hyperalgesia

Status Terminated

Clinical Trial Summary

The purpose of the study is to determine the efficacy of etoricoxib on pain patients. The investigators assume that patients with neuropathic pain will have greater pain relief then patients on placebo.

Clinical Trial Description

Animal experiments analysing anti-hyperalgesic effects of Coxibs show inconsistent results due to different used dosages and varying different pain models. Theoretical the use of NSAIDs is rational, particularly of Coxibs as a part of the neuropathic pain management. But in the newest topical review, there is no valid information available about the effectiveness of these drugs in human neuropathic pain models or in patients with different underlying mechanism, e.g. with or without hyperalgesia. ;

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator), Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01088256
Study type	Interventional
Source	Ruhr University of Bochum
Contact
Status	Terminated
Phase	Phase 2
Start date	February 2011
Completion date	August 2012

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT04546334` - Erector Spinae Plane Block in Post-herpetic Neuralgia	N/A
Terminated	`NCT01744522` - Leech Therapy for Postherpetic Neuralgia	N/A
Completed	`NCT01688947` - Analgesic Efficacy and Safety of V116517 in Subjects With Moderate to Severe Chronic Pain Due to Postherpetic Neuralgia (PHN)	Phase 2
Completed	`NCT00478179` - Study of a Bupivacaine Patch (Eladur™) to Treat Post- Herpetic Neuralgia	Phase 2
Completed	`NCT00566904` - New Topical Treatment for Continued Pain After Shingles	Phase 1
Completed	`NCT04099706` - Treatment of Chronic Postherpetic Pain With Autologous Fat Grafting - A RCT	N/A
Terminated	`NCT01603394` - Pilot Study Of Pregabalin And Prediction Of Treatment Response In Patients With Postherpetic Neuralgia	Phase 4
Completed	`NCT01251211` - Botulinum Toxin in Peripheral Neuropathic Pain	Phase 4
Completed	`NCT01228838` - Study of NGX-1998 for the Treatment of Postherpetic Neuralgia	Phase 2
Completed	`NCT00612105` - Safety/Efficacy Study of Retigabine vs. Placebo in Post-Herpetic Neuralgia (PHN)	Phase 2
Recruiting	`NCT04560361` - The Analgesic Effect of Electroacupuncture on Postherpetic Neuralgia	N/A
Recruiting	`NCT05568186` - Correlation Between Thermal Patterns of Infrared Thermal Imaging and Clinical Phenotype in Patients With Postherpetic Neuralgia
Recruiting	`NCT04664530` - The Study on the Esketamine in the Treatment of Postherpetic Neuralgia	Phase 4
Active, not recruiting	`NCT01508676` - Effects of Pennsaid on Clinical Neuropathic Pain	N/A
Completed	`NCT00885586` - Acupuncture in Herpes Zoster Neuralgia (ACUZoster)	Phase 4
Completed	`NCT00981227` - Efficacy and Safety of Eslicarbazepine Acetate as Therapy for Patients With Post-Herpetic Neuralgia	Phase 2
Completed	`NCT00576108` - A 2 Week Study of Topical KD7040 in the Treatment of Postherpetic Neuralgia (PHN)	Phase 2
Completed	`NCT00238511` - An Open-Label Follow-on Trial to Assess the Long-Term Safety and Efficacy of Oral SPM 927 in Subjects With Postherpetic Neuralgia (PHN)	Phase 2
Completed	`NCT00007501` - Shingles Prevention Study	Phase 3
Completed	`NCT04594226` - Electroacupuncture Therapy for Treating Postherpetic Neuralgia	N/A