Cathartic Colon Clinical Trial
Official title:
Efficacy of Reduced Volume Oral Sulfate Solution (SUPREP) Compared With PEG Plus Ascorbic Acid for Screening Colonoscopy: Single Center, Single Blinded Prospective Randomized Study
The aims of the present study is to compare oral sulfate solution (OSS) with low-dose polyethylene glycol plus ascorbic acid (2-L PEG/Asc) for bowel cleansing efficacy.
High-quality bowel cleansing is critical to effective colonoscopy. Studies in the past decade
have demonstrated that many clinical practices continue to have rates of adequate preparation
as low as 60% to 80%.
Low-volume preparations for colonoscopy are designed to improve patient tolerability, another
important aspect of bowel preparation. In addition, low-volume preparations should ideally
not sacrifice efficacy. There are few data comparing the efficacy of available low-volume
bowel preparations.
In this study, we describe a prospective, single-blind, randomized, controlled trial
comparing oral sulfate solution (OSS) (SUPREP, Braintree Laboratories, Braintree, Mass) with
low-dose polyethylene glycol plus ascorbic acid (2-L PEG/Asc).
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