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Cataracts clinical trials

View clinical trials related to Cataracts.

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NCT ID: NCT01001806 Completed - Cataracts Clinical Trials

A Comparison of Peak Aqueous Penetration of Acuvail (Ketorolac 0.45%), Xibrom (Bromfenac 0.09%), and Nevanac (Nepafenac 0.1%)in Patients Undergoing Phacoemulsification

Start date: October 2009
Phase: Phase 4
Study type: Interventional

Approximately 126 subjects scheduled to undergo cataract surgery by phacoemulsification, will be randomized in an even allocation (1:1:1) to either Acuvail, Xibrom, or Nevanac. Subjects will be instructed to begin dosing the study medication in the operative eye the day before surgery and continue dosing on the day of surgery. Beginning one hour before surgery, 1 drop of study medication will be instilled by operating room staff approximately every 15 minutes for a total of 3 doses. At the designated time a paracentesis will be performed at the start of the cataract procedure and at least 0.15 cc of aqueous humor will be collected. The sample will be immediately stored on dry ice and shipped to a laboratory for analysis.

NCT ID: NCT00999492 Completed - Cataracts Clinical Trials

Selection of Aspheric Diffractive Multifocal Intraocular Lens (IOLS) Based on Corneal Wavefront

Start date: October 2009
Phase: Phase 4
Study type: Interventional

Given the availability of aspheric diffractive IOLs with varying negative spherical aberration it may be feasible, by selecting the best fit IOL, to minimize aberrations and thereby maximize visual performance.

NCT ID: NCT00921297 Completed - Alzheimer's Disease Clinical Trials

Cataract Removal and Alzheimer's Disease

Start date: June 2009
Phase: N/A
Study type: Interventional

Two very common aging-related diseases in older adults are Alzheimer's disease (AD) and cataracts. In elderly adults, these two diseases frequently occur in the same person. Although a cure for AD is currently unavailable, cataracts can be effectively treated with surgery in most people. The removal of cataracts has documented benefits for visual performance and for reducing accidents and falls. However, it has been the experience of the ophthalmologists, and others in the field, that patients, caregivers, and primary care doctors are reluctant to proceed with cataract surgery once an individual is given the diagnosis of AD. It is thought that cataract surgery will not improve the AD patient's quality of life, vision, and cognition. The investigators have designed this study to determine whether or not this is true.

NCT ID: NCT00845520 Completed - Cataracts Clinical Trials

Safety and Effectiveness of the Calhoun Vision Light Adjustable Intraocular Lens (LAL)

Start date: January 2009
Phase: N/A
Study type: Interventional

The primary objective of this study is to evaluate, for the visual correction of aphakia, the safety and effectiveness of the Calhoun Vision Light Adjustable intraocular lens (LAL) and Light Delivery Device (LDD) in treating postoperative residual refractive error by providing a stable, targeted refractive adjustment of the LAL power and lock-in treatments with the LDD.

NCT ID: NCT00827073 Completed - Cataracts Clinical Trials

Comparison of Tetracaine 0.5% and Lidocaine 2% Jelly for Topical Phacoemulsification Cataract Surgery

Start date: November 2008
Phase: N/A
Study type: Interventional

The purpose of this study is to determine if there is a difference on the penetration of betadine 5% when using lidocaine 2% jelly versus topical tetracaine 0.5% in topical cataract surgery. This will be assessed comparing bacterial colony count and species by taking swabs from the eye surface before and after the topical anesthesia has been administered.

NCT ID: NCT00818116 Completed - Cataracts Clinical Trials

Visual Function Evaluation of Bilateral AcrySof ReSTOR Aspheric IOL

Start date: December 2008
Phase: Phase 4
Study type: Interventional

The objective of this study is to evaluate postoperative visual function in patients implanted bilaterally with the ReSTOR Aspheric Intraocular Lens (IOL).

NCT ID: NCT00758199 Completed - Cataracts Clinical Trials

Determination of Optimum Duration of Treatment With Bromfenac (Xibrom) Eyedrops Following Cataract Surgery

Start date: July 2008
Phase: Phase 4
Study type: Interventional

The objective of this study is to determine if an extension of bromfenac BID monotherapy is effective in the decreasing retinal thickening post cataract IOL placement surgery. No studies exist on how long to treat with an NSAID post cataract IOL placement surgery. Currently, NSAID therapy post IOL placement surgery is in conjunction with steroid treatment, lasting approximately 3 weeks. This study is designed to examine if there is benefit to extending NSAID monotherapy in regards to macular thickening and the incidence of CME.

NCT ID: NCT00732225 Completed - Cataracts Clinical Trials

DisCoVisc Comparative Evaluation

Start date: May 2007
Phase: Phase 3
Study type: Interventional

A comparison of the ability of DisCoVisc to that of other Opthalmic Viscosurgical Devices (OVDs) (DuoVisc®, BioVisc®, Healon5®, or Amvisc PLUS) regarding endothelial protection and anterior chamber space maintenance during non-eventful cataract surgery.

NCT ID: NCT00732030 Completed - Cataracts Clinical Trials

Low Cylinder Toric

Start date: June 2007
Phase: Phase 4
Study type: Interventional

Study evaluates the visual outcomes and patient satisfaction after implantation of a toric intraocular lens (IOL).

NCT ID: NCT00731640 Completed - Cataracts Clinical Trials

Contralateral ReSTOR / Monofocal or Phakic Eye

Start date: June 2007
Phase: Phase 4
Study type: Interventional

Bilateral evaluation of unilateral implantation of ReSTOR and contralateral monofocal or phakic eye.