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Clinical Trial Summary

The purpose of the proposed investigation is to carry out a pilot study of add-on perampanel (Fycompa) in women with perimenstural (C1) catamenial epilepsy. Perampanel, a noncompetitive AMPA receptor antagonist, is uniquely positioned to decrease progesterone receptor mediated excitotoxicity. This mechanism of action would allow a novel use of perampanel as an effective treatment of C1 catamenial epilepsy.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05201703
Study type Interventional
Source University of Florida
Contact
Status Not yet recruiting
Phase Phase 4
Start date March 2022
Completion date January 2023

See also
  Status Clinical Trial Phase
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Withdrawn NCT00559169 - Verapamil and Catamenial Epilepsy N/A
Completed NCT00465517 - A Randomized, Controlled Trial of Ganaxolone in Adult Uncontrolled Partial-Onset Seizures Phase 2