Clinical Trials Logo

Clinical Trial Summary

The Hyalex First-in-Human Study is a prospective, multicenter, open-label, single-arm, 2-phase, first-in-human study to evaluate the safety and technical performance of the HYALEX Knee Cartilage System for replacement of loss of articular cartilage and bone of the knee femoral condyles in symptomatic patients who require surgical treatment.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT06344481
Study type Interventional
Source Hyalex Orthopaedics, Inc.
Contact Chris Cain
Phone 408-439-5154
Email chris.cain@hyalex.com
Status Recruiting
Phase Phase 1
Start date March 7, 2024
Completion date September 2026

See also
  Status Clinical Trial Phase
Recruiting NCT03479775 - Muscle Function and Traumatic Knee Injury in Sports
Recruiting NCT03321812 - Clinical Study of Decalcification Bone Scaffold for Cartilage Lesions of the Knee N/A
Recruiting NCT06082531 - Effect of Platelet-rich Plasma (PRP) Injection on Knee Osteoarthritis N/A
Completed NCT06078072 - Biomaterials and Mesenchymal Stem/Stromal Cells in the Treatment of Knee Articular Surface Lesions
Completed NCT04889443 - Spontaneous Healing of ARticular Cartilage (SHARC)
Completed NCT04118023 - 7T MRI to Evaluate Cartilage Defects in the Knee
Active, not recruiting NCT01458782 - ACI-C Versus AMIC. A Randomized Trial Comparing Two Methods for Repair of Cartilage Defects in the Knee N/A
Recruiting NCT03477942 - Impact of Mesenchymal Stem Cells in Knee Osteoarthritis Phase 1
Completed NCT01473199 - BioPoly RS Knee Registry Study for Cartilage Defect Replacement N/A
Recruiting NCT05124613 - The Impact of Covid-19 on Patients Waiting for Knee Surgery
Completed NCT04739930 - Autologous Bone Marrow Concentrate in Knee Osteochondral Allograft Transplantation N/A
Active, not recruiting NCT03873545 - Prospective Evaluation of ProChondrix CR for Repair of Articular Cartilage Defects on Femoral Condyle and Patella
Recruiting NCT05328674 - Clinical and Comparative Evaluation of the Treatment Results of Arthroscopic Reconstruction of Cartilage Defects in the Knee Joint With the Use of Autogenous Cartilage Graft With PRP GF (Platelet-rich Plasma With Growth Factors) N/A
Recruiting NCT04184687 - The Treatment of Cartilaginous Lesions and Concomitant Anterior Cruciate Ligament Reconstruction N/A
Terminated NCT04301258 - ProChondrix® CR Articular Cartilage Restoration Evaluation (PACE) Registry
Completed NCT02696876 - Synovium Brushing to Augmented Microfracture for Improved Cartilage Repair N/A
Completed NCT02637505 - Norwegian Cartilage Project - Microfracture N/A
Recruiting NCT04135950 - Prospective Registry of Anterior Cruciate Ligament Reconstructions
Completed NCT03024801 - Effectiveness of Autologous Platelet-rich Plasma on Knee Cartilage Injury N/A
Completed NCT01041001 - Study to Compare Efficacy and Safety of Cartistem and Microfracture in Patients With Knee Articular Cartilage Injury Phase 3