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Carpal Tunnel Syndrome clinical trials

View clinical trials related to Carpal Tunnel Syndrome.

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NCT ID: NCT05094778 Completed - Clinical trials for Carpal Tunnel Syndrome

A Single-portal Endoscopic Approach Through Subcutaneous Tunnel for Carpal Tunnel Release

Start date: January 5, 2012
Phase: N/A
Study type: Interventional

Traditional endoscopic release directly accesses the carpal tunnel and thus carries a higher risk of nerve irritability, even nerve injury. Based on our anatomical study, the investigators developed a new endoscopic technique through a single-portal palm approach that passes superficially to palmar aponeurosis, and cut the full transverse carpal ligament. The investigators will compared the technique with the standard dual-portal endoscopic technique.

NCT ID: NCT05086042 Completed - Clinical trials for Carpal Tunnel Syndrome

Carpal Tunnel Syndrome in Patients With Psoriatic Arthritis; Ultrasonography and Magnetic Resonance Imaging Findings

Start date: March 15, 2019
Phase:
Study type: Observational

This study aimed to investigate relationship between CTS diagnosis with electrodiagnostic studies and median nerve's cross-sectional area measered by US and MRI in PsA patients.

NCT ID: NCT05086029 Completed - Clinical trials for Carpal Tunnel Syndrome

Carpal Tunnel Syndrome in Patients With Psoriatic Arthritis

Start date: March 20, 2019
Phase:
Study type: Observational

This study aimed to investigate median nerve hypervasculatitation in psoriatic arthritis (PsA) patients with CTS or without CTS by using SMI, then compare them with normal people.

NCT ID: NCT05067205 Completed - Clinical trials for Carpal Tunnel Syndrome

Minimal Invasive Carpal Tunnel Release With the Novel Device

Start date: September 8, 2021
Phase: N/A
Study type: Interventional

This is a prospective, open-label, parallel-group, randomized controlled trial to evaluate the postoperative outcome after carpal tunnel release by using mini CTS releaser and open method with duration of 6 months estimated. The study hypothesis is that mini CTS releaser can offer similar functional outcomes to the open approach and avoid the complications of the open surgery.

NCT ID: NCT05057754 Completed - Clinical trials for Carpal Tunnel Syndrome

Sonographic Measurement of Intraneural Blood Flow in the Median Nerve

Start date: December 13, 2021
Phase: N/A
Study type: Interventional

Carpal tunnel syndrome (CTS) is the most common nerve compression disease and the most expensive upper-extremity work-related musculoskeletal disorder, affecting approximately 10 million people in the US. To understand the clear etiology and mechanism of carpal tunnel syndrome, the measurement of median nerve intraneural blood flow needs to be further scrutinized as the common fluctuating physiological conditions and functional hand activities might contribute to the fluctuation of the measurement and serve as measurement error. This study aims to examine how intraneural blood flow within the median nerve is affected by physiological factors (i.e., body temperature and blood pressure) and functional hand activities (i.e., typing, using a mouse, and cooking).

NCT ID: NCT05053477 Recruiting - Clinical trials for Carpal Tunnel Syndrome

Radiofrequency, Perineural Injection, Idiopathic Carpal Tunnel Syndrome

Start date: September 1, 2018
Phase: Phase 1
Study type: Interventional

Aim of the study The aim of the study is to evaluate the role of pulsed radiofrequency versus platelet rich plasma injection in treatment of idiopathic mild to moderate carpal tunnel syndrome Patients will be classified into three equal groups using randomized closed envelop method into three groups. Control Group ( n=25):Patients will receive median nerve perineural injection of bupivacaine with mehylprednisolone under ultrasound guidance. PRF Group ( n=25):Patients will receive median nerve pulsed radiofrequency (PRF) and median nerve perineural injection of bupivacaine under ultrasound guidance PRP Group (n=25): Patients will receive median nerve perineural injection of platelet-rich plasma (PRP) under ultrasound guidance Measurements (will be done before the procedure, one week ,two month and four months after procedure except SNCV and serum CRP and TNF α (tumor necrosis factor alpha)will be done before the procedure and after four months only): 1. VAS (visual analogue pain scale) 2. BCTQ (Boston carpal tunnel Questionnaire) 3. Degree of paresthesia tested by Reverse Phalen's test. 4. CSA (cross sectional area)0 of the median nerve will be measured by the same pain therapist involved in the study. 5. SNCV (nerve conduction velocity study): performed by same physiotherapist not involved in the study before and after intervention. 6. Serum Tumor necrosis factor alpha (TNF α). 7. C-reactive protein (CRP) 8. Complications will be recorded and managed. Items 1,2 and 3 will be measured by a pain therapist not involved in this study

NCT ID: NCT05047367 Completed - Anxiety Clinical Trials

The Relationship of Psychological Factors and Sleep Quality With the Severity of Carpal Tunnel Syndrome

Start date: January 13, 2021
Phase:
Study type: Observational [Patient Registry]

The most common entrapment neuropathy symptoms, the diagnosis of CTS, is determined by examination findings and by means of the results of electro-diagnostic test. With an increase in disease severity, trap neuropathy, whose symptoms are more pronounced at night, negatively affects the daily life of the person. Deterioration in sleep quality may cause depression and anxiety. Conflicting results have been found in the studies related to these findings. However, no study was found in which daytime sleepiness was evaluated in terms of CTS. The investigators aim in this study is to evaluate the relationship between CTS severity and depression, anxiety, sleep quality and daytime sleepiness.

NCT ID: NCT05031338 Terminated - Clinical trials for Carpal Tunnel Syndrome

Carpal Tunnel Release Using Ultrasound

CiTRUS
Start date: July 2, 2021
Phase:
Study type: Observational [Patient Registry]

The goal of the Carpal Tunnel Release Using Ultrasound registry (CiTRUS Registry) is to collect experience information from patients scheduled to undergo carpal tunnel release surgery with either the SX-One MicroKnife® with ultrasound guidance or the traditional mini-open technique without US guidance.

NCT ID: NCT05023603 Completed - Clinical trials for Carpal Tunnel Syndrome

Social and Cognitive Factors in Carpal Tunnel Syndrome

Start date: October 25, 2021
Phase:
Study type: Observational [Patient Registry]

Carpal tunnel syndrome (CTS) is a compressive peripheral neuropathy, characterized by pain, tingling sensation and paresthesia in the territory of the median nerve, symptoms modulated by psychosocial factors (eg, catastrophic thinking, depression, anxiety). The objective of the study is to determine those psychological and social components that influence the symptoms and function of patients with CTS. An observational cross-sectional design will be performed in patients with CTS. The patients will be selected consecutively in two hospitals of the South East Metropolitan Health Service (Santiago, Chile). The study variables will include: Perception of pain using the Visual Analogue Scale (VAS), the extent of symptoms will be evaluated using the Katz diagram; Functional assessment using the abbreviated version of the Disabilities of the Arm, Shoulder and Hand Questionnaire (QuickDASH); Catastrophic thinking as a response to pain using the Pain Catastrophizing Scale (PCS), fear of movement using the Tampa Scale for Kinesiophobia (TSK-11), and emotional state was assessed using the Hospital Anxiety and Depression Scale (HADS). Both are valid and reliable measures used to evaluate the influence of psychosocial factors in patients with CTS. Individual subject factors including duration of symptoms, type of work (desk / non-desk), BMI, age, gender, educational level and economic income will be collected through an interview process.

NCT ID: NCT05017467 Completed - Clinical trials for To Prevent Scar Formation for Patients Underwent Surgery

The Effect of Centella Asiatica Cream on Scar Tenderness Who Underwent Open Carpal Tunnel Release Surgery

Start date: January 1, 2011
Phase: Early Phase 1
Study type: Interventional

The centella asiatica cream applied to the wrist after the CTR surgery was found to be beneficial in preventing the scar tenderness in the thenar and hypothenar regions of the hand.