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Clinical Trial Summary

The aim of the study is to assess the viability and efficacy of carbon dioxide laser in combination with a fluoride varnish in the prevention, severity, and extent of white spot lesions during orthodontic treatment with fixed appliances.


Clinical Trial Description

White spot lesions associated with orthodontic treatment are a common problem. The carbon dioxide laser is reported to be the most effective one in the prevention of dental caries. The study is designed as a randomized, split-mouth controlled, clinical trial. The participants will be children aged 12-18 years at high caries risk, requiring fixed orthodontic treatment. The vestibular surfaces of the maxillary anterior teeth of the eligible patients will be exposed to carbon dioxide laser irradiation in combination with fluoride therapy and fluoride therapy alone followed by bonding of orthodontic brackets. The patients will be recalled 6 and 12 months post-irradiation. Outcome measures will be visual examination with the International Caries Detection and Assessment System (ICDAS) criteria and SoproLife ® Daylight and Blue fluorescence. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04903275
Study type Interventional
Source Plovdiv Medical University
Contact Maria Shindova, PhD
Phone 00359898390935
Email mariya.shindova@gmail.com
Status Not yet recruiting
Phase N/A
Start date September 1, 2021
Completion date August 1, 2023

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