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Caries; Initial clinical trials

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NCT ID: NCT05969756 Recruiting - Caries,Dental Clinical Trials

Early Treatments for Preventing Occlusal Caries Lesions

Start date: July 31, 2023
Phase: N/A
Study type: Interventional

Sealants effectively arrest non-cavitated caries lesions on the fully erupted occlusal surface of permanent teeth. However, the clinical effectiveness of sealants is uncertain in preventing occlusal caries lesions in partially erupted permanent molars. This study aims to evaluate the progression of caries, the degree of retention, survival rate, and quality of the remnant after applying conventional total-etch resinous sealant and self-etch sealant in erupting molars.

NCT ID: NCT05891288 Not yet recruiting - Caries; Initial Clinical Trials

Sealing of Initial Occlusal Caries Using Fissure Sealants

Start date: July 1, 2023
Phase: N/A
Study type: Interventional

The purpose of this study is to compare the performance of newly introduced bioactive resin based pits and fissure sealant versus fluoride releasing resin based pits and fissure sealant in initial carious lesions of fissures in posterior molars in patients at risk of caries. Visual tactile examination and VistaCAM will be used for evaluation.

NCT ID: NCT05127356 Completed - Caries; Initial Clinical Trials

Diagnostic Accuracy of DIAGNOdent Compared to ICDAS II

Start date: February 1, 2022
Phase:
Study type: Observational

There is a paradigm shift in conservative dentistry by substituting the surgical model with the medical model of treatment. Early detection of initial carious lesions will aid in clinical decision making during management ; either no care advised, preventive care advised or operative care advised. According to recent systematic reviews meticulous visual examination using ICDAS II presented a substantial level of reproducibility and accuracy for assessment of carious lesions and was considered the reference for clinical visual assessment . However, visual examination is subjective and is highly dependent on the dentist's skills and experience, with high specificity and low sensitivity. New devices have been developed to detect and quantify incipient demineralization. Besides visual detection systems, laser fluorescence assessment can be considered a suitable method. In vitro data suggested that the visual examination and fluorescence method have similar accuracy to detect initial carious lesions.

NCT ID: NCT05094492 Not yet recruiting - Caries; Initial Clinical Trials

Evaluation of Remineralization Potential of Self Assembling Peptide Combined With Fluoride

Start date: October 30, 2021
Phase: N/A
Study type: Interventional

Self-assembling peptide (P11-4) exhibited an outstanding ability for biomimetic re-mineralization of incipient enamel carious lesions. It creates a 3D matrix within the subsurface of carious lesions, allowing de novo formation of Hydroxyapatite crystals, thus enabling guided enamel regeneration of the demineralized enamel structure. Addition of fluoride to P11-4 may have a synergistic effect on the remineralization potential.

NCT ID: NCT04929327 Not yet recruiting - Caries; Initial Clinical Trials

Retention Rate of Self-etch Resin Based Sealant With and Without Prior Sandblasting

Start date: July 2021
Phase: N/A
Study type: Interventional

The aim of the study is to clinically assess the effect of sandblasting prior to self-etch resin based sealant on its retention after one year follow up.

NCT ID: NCT04903275 Not yet recruiting - Caries; Initial Clinical Trials

Caries Inhibition With CO2-Laser During Orthodontic Treatment

Start date: September 1, 2021
Phase: N/A
Study type: Interventional

The aim of the study is to assess the viability and efficacy of carbon dioxide laser in combination with a fluoride varnish in the prevention, severity, and extent of white spot lesions during orthodontic treatment with fixed appliances.

NCT ID: NCT04092296 Recruiting - Caries; Initial Clinical Trials

Efficacy of Resin Infiltration of Proximal Caries

RIDCBW
Start date: August 10, 2018
Phase: N/A
Study type: Interventional

The aim of the present study was to assess the clinical efficacy of resin infiltration of interproximal caries lesions using a novel measure method-----DIAGNOcam. This study is conducted on adults (15-40y)with the aim of comparing the therapeutic effects of infiltrating caries lesions and fluoride remineralization treatment after 1, 2, and 3 yrs. The outcome (lesion progression) is evaluated by DIAGNOcam and radiographic techniques.And we would compare the sensitivity of monitoring progression of caries between DIAGNOcam and bitewing radiography.