Clinical Trials Logo
  1. Home
  2. Cardiovascular Events
  3. NCT03391128

Circulating P3NP and Cardiovascular Events in Hemodialysis Patients

Cardiovascular Events Clinical Trial

Official title:
Involvement of Circulating Aminoterminal Propeptide of Type 3 Procollagen in Cardiovascular Events in Patients on Hemodialysis

Clinical Trial Summary

This study evaluates whether circulating levels of aminoterminal propeptide of type III procollagen (PIIINP) can predict the cardiovascular events in hemodialysis patients.

Clinical Trial Description

Type III collagen abundantly exists in the cardiovascular system including the aorta and heart. The aminoterminal propeptide of type III procollagen (PIIINP) is an extension peptide of type III procollagen, which is cleaved off stoichiometrically during conversion from type III procollagen to type III collagen and liberated to serum. Elevated serum concentrations of PIIINP are considered a marker of higher collagen turnover and tissue fibrosis including the heart and vascular system. In this study, the investigators prospectively examined whether serum levels of PIIINP could be a biomarker for predicting cardiovascular events in hemodialysis patients. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03391128
Study type Observational
Source Toujinkai Hospital
Contact
Status Completed
Phase N/A
Start date January 1, 2005
Completion date January 31, 2005
View Details
See also
  Status Clinical Trial Phase
Recruiting NCT01589536 - Social Medical Progression of Coronary Heart Disease With Associated Psychosocial Comorbidity -Interval Rehabilitation. N/A
Completed NCT03798457 - Incidence and Prognostic Implication of Acute CV Events in Patients Hospitalized for CAP in Internal Medicine Units.
Completed NCT01223586 - Extended Japan Assessment of Pitavastatin and Atorvastatin in Acute Coronary Syndrome N/A
Recruiting NCT05985447 - Menopause Related Influences on Leukocyte Distribution, Monocyte Function and Platelet Reactivity
Recruiting NCT05457582 - PCSK 9 Inhibitor Added to High-Intensity Statin Therapy to Prevent Cardiovascular Events in Patients With ACS After PCI N/A
Completed NCT01755078 - Long Term Evaluation of Sevelamer HCl vs. Calcium-based Phosphate Binder in the Treatment of Hyperphosphatemia in Hemodialysis Patients Phase 4
Recruiting NCT04183426 - Tonometry(1) and Duplex Ultrasound(2) to Predict CV Events in to be Treated Patients With an AAA
Recruiting NCT03154203 - Non-Invasive Aortic Ambulatory Blood Pressure Monitoring for The Detection of Target Organ Damage in The Chinese Population N/A
Completed NCT03989011 - Tonometry and Duplex Ultrasound to Predict AAA Progression and CV Events in Aneurysm Patients (1-2-3 Trial)
Terminated NCT01259297 - A Randomized Controlled Trial of Aliskiren in the Prevention of Major Cardiovascular Events in Elderly People Phase 3
Completed NCT01395550 - Secondary Prevention Treatment in Patients Who Have Suffered a Cardiovascular Event N/A
Completed NCT04776226 - Post-stroke Depression Treatment Effect on Stroke Recurrence N/A
Recruiting NCT06029933 - Fluad vs. Fluzone High-Dose Vaccine Effectiveness Among Adults ≥65 Years
Active, not recruiting NCT05220917 - Comparative Effectiveness and Safety of Four Second Line Pharmacological Strategies in Type 2 Diabetes Study
Active, not recruiting NCT05063097 - Addiction in Intensive Cardiac Care Units
Not yet recruiting NCT06333574 - Weight Management of Dialysis Patients N/A