Cardiopulmonary Clinical Trial
Official title:
Effect of Indoor Plants on Cardiopulmonary System: a Randomized, Crossover, Controlled Trial
This is a randomized controlled human exposure crossover study, aims to explore the health benefits of indoor plants on cardiopulmonary system on adults.
Status | Not yet recruiting |
Enrollment | 48 |
Est. completion date | January 13, 2024 |
Est. primary completion date | January 13, 2024 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 18 Years to 35 Years |
Eligibility | Inclusion Criteria: - Living in Hangzhou during the study period; - Non-smoking, no history of alcohol or drug abuse; - Staying indoors in daytime we required. Exclusion Criteria: - Current or ever smokers; - Subjects with allergic disease, such as allergic rhinitis, allergic asthma, and atopy; - Subjects with cardiovascular disease, such as congenital heart disease, pulmonary heart disease, and hypertension; - Subjects with respiratory disease, such as asthma, chronic bronchitis, and chronic obstructive pulmonary disease; - Subjects with chronic disease, such as diabetes, chronic hepatitis, and kidney disease; - Subjects with a history of major surgery; - Medication use or dietary supplements intake in recent two months; - Unable to cooperate with follow-up. |
Country | Name | City | State |
---|---|---|---|
n/a |
Lead Sponsor | Collaborator |
---|---|
Lina Zhang | Zhejiang Chinese Medical University |
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Other | C-reactive protein(CRP) | We plan to measure serum concentrations of C-reactive protein(CRP) | Baseline and after 4 weeks plants exposure in first stage, and after washout period, baseline and after 4 weeks plants exposure in second stage. | |
Other | Interleukin-6(IL-6) | We plan to measure the serum concentrations of Interleukin-6 | Baseline and after 4 weeks plants exposure in first stage, and after washout period, baseline and after 4 weeks plants exposure in second stage. | |
Other | Tumor necrosis factor-a(TNF-a) | We plan to measure the serum concentrations of Tumor necrosis factor-a | Time Frame: Baseline and after 4 weeks plants exposure in first stage, and after washout period, baseline and after 4 weeks plants exposure in second stage. | |
Primary | Forced Vital Capacity(FVC) | We plan to measure forced vital capacity (FVC) of lung function. | Baseline and after 4 weeks plants exposure in first stage, and after washout period, baseline and after 4 weeks plants exposure in second stage. | |
Secondary | Blood Pressure(BP) | We plan to measure systolic blood pressure (SBP) and diastolic blood pressure (DBP). | Baseline and after 4 weeks plants exposure in first stage, and after washout period, baseline and after 4 weeks plants exposure in second stage. | |
Secondary | Heart Rate Variability(HRV) | We plan to measure Heart Rate Variability (HRV). | Baseline and after 4 weeks plants exposure in first stage, and after washout period, baseline and after 4 weeks plants exposure in second stage. |
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