Quality of the Cardio-pulmonary Resuscitation

Cardiopulmonary Resuscitation Clinical Trial

Official title:

Cardiopulmonary Resuscitation; Epidemiology, Quality, Survival and Injuries.

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT05250453
• Other study ID #: R18100
• Secondary ID: R18163R21124
• Status: Recruiting
• Start date: January 1, 2022
• Est. completion date: July 1, 2023

Study information

• Verified date: February 2022
• Source: Tampere University Hospital
• Contact: Sanna Hoppu, PhD
• Phone: +3583311611
• Email: sanna.hoppu[@]pshp.fi
• Is FDA regulated: No
• Study type: Observational [Patient Registry]

Clinical Trial Summary

Patients having sudden cardiac arrest have very poor prognosis. It is devastating for patient and family. But also very expensive for nations economics when working-age people die or disable due to cardiac arrest. Recent studies have shown that high quality of cardiopulmonary resuscitation (CPR) and minimized delays increases the survival after cardiac arrest. In this objective prospective study we will use Zoll´s X Series defibrillator on every emergency medicine systems (EMS´s) unit in Pirkanmaa area, Finland, to collect information on CPR quality. Real CPR Help® will collect the information on depth, frequency and pauses during CPR. We will make an Utstein analysis on OHCA during one year period and compare the results on Utstein analysis made in the same area on 2013-2014. We will analyse the quality of CPR and compare it to the outcome from OHCA and neurological outcome 3 months after resuscitation. In addition we will analyse the CPR related injuries and compare these to the compression depth and number of persons performing CPR.

In one part of the study we will evaluate the incidence of OHCA in different risk areas of Pirkanmaa and analyse the influence of time delay and location to the outcome out of hospital and neurological outcome 3 months after resuscitation. We will also analyse if the time of post-resuscitation care before getting to the hospital or stenosis in carotid artery affects the outcome from OHCA and neurological outcome 3 months after resuscitation.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 400
• Est. completion date: July 1, 2023
• Est. primary completion date: March 31, 2023
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 100 Years

Eligibility

Inclusion Criteria:

• cardiac arrest

• > 18 years of age

Exclusion Criteria:

• < 18 years of age

• prisoners

Related Conditions & MeSH terms

• Cardiopulmonary Resuscitation

Locations

Country	Name	City	State
Finland	Tampere University hospital	Tampere

Sponsors (2)

Lead Sponsor	Collaborator
Tampere University Hospital	National Istitute For Health and Welfare, Finland

Country where clinical trial is conducted

Finland, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	QualityCPR	The success rate of current guidelines (depth and frequency of chest compression, epidemiology)	1 year
Primary	Neurological survival after CA	Neurological survival after CA	3 months after OHCA
Secondary	CPR related injuries	Injuries detected in CT scanning or in autopsy	1 year
Secondary	Stenosis of the carotid artery	Effect of the carotid artery stenosis to the neurological survival. Survivals having CPC 1-2 prior to the cardiac arrest and are taken to the ICU are scanned with carotid CTA after informed consent. The degree of stenosis will be compared to the CPC-level 3monts aften OHCA.	3 months after OHCA
Secondary	the dispatch calls concerning OHCA	Analyze the key words and dispatch assisted CPR through the emergency call. All emergency call conserning OHCA patients will be listened. We will analyze the keywords which are used by layperson to describe patient having cardiac arrest.; We will also analyze the amount of given dispatch assisted CPR and compare the amount to the primary rythm.	1 year
Secondary	the quality of the postresuscitation care	The correlation of the duration and the quality of the postresuscitation care before getting in to the hospital and the outcome from OHCA	3 months after OHCA