Double Anaerobic Threshold in Athletes

Status Recruiting

Clinical Trial Summary

During an incremental cardiopulmonary exercise test (CPET) performed with a ramp protocol, it is very important to determine the anaerobic threshold, defined as the point at which the metabolism switches from being predominantly aerobic to also being anaerobic. The anaerobic threshold can be determined invasively, by identifying the increase in blood lactates with an arterial sampling, or, more commonly, non-invasively by three methods: the V-slope method, the ventilatory equivalents method and by using end-expiratory oxygen and carbon dioxide pressure (PETO2 and PETCO2 respectively). Normally, the anaerobic threshold is determined by the first method and the other two are used to confirm the value. The finding of different anaerobic threshold values using these three methods has been reported anecdotally in the past, while a prevalence of 11% in a healthy population has recently been described. Regular training, particularly that aimed at endurance sports, is able to shift the anaerobic threshold to higher exercise intensities. At present, the physiological reasons for the presence of a double threshold are unclear. The aim of the study is to identify the anaerobic threshold by means of the V-slope method and by means of the ventilatory equivalents method in athletes who have performed an incremental ramp CPET at the laboratories of the investigating centres, to assess in how many athletes a double threshold is present and to try to interpret the physiological/ pathophysiological significance of this finding. In this retrospective and prospective observational study, healthy male and female athletes who have had a cardiopulmonary test at our laboratories from 2007 to the present (retrospectively recruited) and prospectively recruited until the calculated sample size is reached will be enrolled.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05770453
Study type	Observational
Source	Centro Cardiologico Monzino
Contact	Piergiuseppe Agostoni, Prof
Phone	+39 0258002772
Email	piergiuseppe.agostoni@cardiologicomonzino.it
Status	Recruiting
Phase
Start date	March 15, 2022
Completion date	December 2023

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT04150952` - HRV-based Training Effects in Athletes	N/A
Completed	`NCT03285009` - Movement Patterns in Young Volleyball Athletes	N/A
Recruiting	`NCT04710667` - To Explore the Effects of Different Training Periods and Dietary Pattern on the Gut Microbiota, Metabolites and Protein Expression Levels of Strength and Endurance Athletes and to Find Relevant Biological Indicators.
Completed	`NCT03773601` - Objective Sleep Behavior in Relation to a Nigth Competition in Athletes.	N/A
Completed	`NCT06042374` - Core Stabilization Training in Elite Athletes	N/A
Completed	`NCT04852549` - Effects of Oculomotor Exercises on Volleyball Players	N/A
Completed	`NCT06086262` - Hand Grip Strength in Athletic and Non-Athletic Girls at Different Phases of Menstrual Cycle
Completed	`NCT04453566` - Effect of COVID-19 Pandemic on Perceived Stress, Anxiety, Mood, and Training Quality in Elite Athletes.
Active, not recruiting	`NCT04632615` - Sleep Behaviour in Athletes During Home Confinement Due to the Covid-19 Outbreak
Completed	`NCT01770977` - Effects of Phototherapy by Light-emitting Diode Therapy (LEDT) on Clinical, Biochemical and Biomechanical of Muscle Performance in Athletes	N/A
Completed	`NCT04776772` - Health Parameters in Soccer Players and Sedentary Individuals After Consuming a Synbiotic	N/A
Completed	`NCT03893604` - Effects of tDCS on High Level and Recreational Athletes	N/A
Completed	`NCT03901222` - 3D Analysis of the Effects of tDCS (Transcranial Direct Current Stimulation) on a Functional Task in High Level Athletes	N/A
Completed	`NCT03321110` - Effects of Coenzyme Q10 Supplementation on Oxidative Stress, Antioxidant Capacity, Inflammatory Responses, Fatigue Elimination, and Exercise Performance in Athletes	N/A
Completed	`NCT05067426` - The 10/7 HIIT Shock Cycle Study: Effectiveness of 10 HIIT Sessions in 7 Days	N/A
Completed	`NCT03672786` - Gene Expression in Intervened Athletes	N/A
Completed	`NCT06446375` - FIFA 11+ Kids Training Protocol and Physical Performance	N/A
Completed	`NCT03901508` - A Single Session of tDCS (Transcranial Direct Current Stimulation) Improves Endurance for 30 Minutes	N/A