Usefulness of the Evaluation of the ROSC With Carotid Ultrasound During CPR

Cardiopulmonary Arrest Clinical Trial

Official title:

Usefulness of the Evaluation of the Return of Spontaneous Circulation(ROSC) With Carotid Ultrasound During Cardiopulmonary Resuscitation(CPR)

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT04793386
• Other study ID #: 2020-11-116
• Status: Recruiting
• Phase: N/A
• Start date: January 1, 2021
• Est. completion date: March 2022

Study information

• Verified date: February 2021
• Source: Samsung Medical Center
• Contact: Sooyeon Kang, Fellow
• Phone: +821031574718
• Email: syrei3.kang[@]samsung.com
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The current cardiopulmonary resuscitation(CPR) guidelines recommend that the heart rhythm be checked every two minutes during CPR for cardiac arrest patients. Also it is very important to stop compressing the chest in less than 10 seconds when checking heart rhythm and pulse.

However, manual palpation, which is used as a standard for return of spontaneous circulation(ROSC), has been reported that the accuracy is not high in several studies. It is quite often necessary to perform pulse palpation for longer than the 10 second recommended by the guidelines to make a judgment.

Recently, a case study was published in which the presence of spontaneous circulation was confirmed by evaluating the carotid artery compressibility and pulsatility with an ultrasound probe when checking the rhythm of cardiac arrest patients. However, there has been no clinical study on actual cardiac arrest patients.

Description:

The current cardiopulmonary resuscitation(CPR) guidelines recommend that the heart rhythm be checked every two minutes during CPR for cardiac arrest patients. Also it is very important to stop compressing the chest in less than 10 seconds when checking heart rhythm and pulse.

However, manual palpation, which is used as a standard for return of spontaneous circulation(ROSC), has been reported that the accuracy is not high in several studies. It is quite often necessary to perform pulse palpation for longer than the 10 second recommended by the guidelines to make a judgment.

Ultrasound is a key technique that guides to discern and treat causes of cardiac arrest patients. Recently, a case study was published in which the presence of spontaneous circulation was confirmed by evaluating the carotid artery compressibility and pulsatility with an ultrasound probe when checking the rhythm of cardiac arrest patients.

However, this is just a case study. There has been no clinical study on actual cardiac arrest patients whether it is possible to accurately determine the ROSC by evaluating the carotid artery compressibility and pulsatility by ultrasound. Also there has been no clinical studies on actual cardiac arrest patients comparing the time taken to evaluate the ROSC of carotid ultrasound and manual palpation.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 23
• Est. completion date: March 2022
• Est. primary completion date: December 2021
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Patients who underwent CPR among cardiac arrest patients 18 years of age or older who visit the emergency room

• Patients who applied carotid ultrasound to determine the presence of carotid artery compression and pulse

Exclusion Criteria:

• Patients who have stated their intention to do not resuscitation for future treatment (including cardiopulmonary resuscitation)

• Patients who have difficulty applying carotid ultrasound due to head and neck trauma

• Patients who have difficulty applying carotid ultrasound due to deformed neck structure by surgery or head and neck cancer

• Return of spontaneous circulation before ultrasound application

• Patients who could not evaluate carotid artery compressibility and pulsatility by ultrasound

Related Conditions & MeSH terms

• Cardiopulmonary Arrest
• Heart Arrest

Intervention

Diagnostic Test:
• carotid ultrasound
Every time checking pulse, evaluate the carotid artery compressibility and pulsatility by ultrasound

Locations

Country	Name	City	State
Korea, Republic of	Samsung Medical Center	Seoul

Sponsors (1)

Lead Sponsor	Collaborator
Samsung Medical Center

Country where clinical trial is conducted

Korea, Republic of, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Time spent assessing	Time spent assessing return of spontaneous circulation using two methods (manual pulse palpation and carotid ultrasound)	Procedure (during chest compression)
Secondary	Agreement of return of spontaneous circulation	Compare the agreement between two methods (manual pulse palpation and carotid ultrasound) for evaluation of return of spontaneous circulation (ROSC).; The gold standard is arterial blood pressure by arterial catheter. The ROSC is judged when pulsation is detected by manual palpation. The ROSC is judged when carotid artery is not totally compressed or has pulsatility by carotid artery ultrasound.	Procedure (during chest compression)