Cardiomyopathy, Hypertrophic Clinical Trial
Official title:
A Multi-center, Randomized, Placebo-controlled Patient and Investigator-blinded Study to Explore the Efficacy of Oral Sacubitril/Valsartan in Adult Patients With Non-obstructive Hypertrophic Cardiomyopathy (nHCM)
The purpose of this study is to determine if LCZ696 is safe, tolerable and can improve exercise capacity (via improved peak VO2) in non-obstructive HCM patient population over the course of 50 weeks of treatment.
n/a
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT00253682 -
Effects of Highly Active Anti-Retroviral Therapy on Cardiovascular Health in Infants of HIV-Infected Mothers
|
N/A | |
Recruiting |
NCT06034405 -
Analysis of Lumbar Spine Stenosis Specimens for Identification of Transthyretin Cardiac Amyloidosis
|
||
Terminated |
NCT04222101 -
Association of Insulin Resistance and FGF21 on Cardiac Function in Pediatric Dilated Cardiomyopathy
|
N/A | |
Recruiting |
NCT05646056 -
A Noninterventional, Single-Center Feasibility Study to Evaluate Measures of Heart Failure Risk
|
||
Completed |
NCT00692991 -
Using Magnetic Resonance Imaging to Evaluate Heart Vessel Function After Angioplasty or Stent Placement Procedures
|
N/A | |
Withdrawn |
NCT04905173 -
Comparison of Squat-to-Stand Maneuver With Amyl Nitrite, Valsalva, and Exercise Stress Echocardiography in Inducing Latent Left Ventricular Outflow Obstruction in Hypertrophic Cardiomyopathy
|
N/A | |
Recruiting |
NCT03251287 -
Nitrite in Hypertrophic Cardiomyopathy (HCM) Study
|
Phase 1 | |
Recruiting |
NCT01165749 -
Exercise Study Including Patients With Hypertrophic Cardiomyopathy
|
N/A | |
Recruiting |
NCT03057002 -
UTSW HP [13-C] Pyruvate Injection in HCM
|
||
Recruiting |
NCT02696135 -
The Chinese Hypertrophic Cardiomyopathy Study(CHCS)
|
||
Recruiting |
NCT03040947 -
MRI Sequence and Imaging Protocol Development
|
||
Active, not recruiting |
NCT02417311 -
Individualized Early Risk Assessment for Heart Diseases
|
||
Completed |
NCT03225001 -
PARTNER II Trial: Placement of AoRTic TraNscathetER Valves II - Nested Registry 3/Valve-in-Valve
|
N/A | |
Recruiting |
NCT05524077 -
Catheter Ablation Versus Anti-arrhythmic Drugs for Ventricular Tachycardia
|
N/A | |
Recruiting |
NCT06112743 -
A Study to Evaluate Mavacamten Impact on Myocardial Structure in Participants With Symptomatic Obstructive Hypertrophic Cardiomyopathy
|
Phase 4 | |
Completed |
NCT00001871 -
Study of Muscle Abnormalities in Patients With Specific Genetic Mutations
|
N/A | |
Completed |
NCT00001459 -
Analysis of Heart Muscle Function in Patients With Heart Disease and Normal Volunteers
|
N/A | |
Completed |
NCT00005251 -
Genetic Analysis of Familial Hypertrophic Cardiomyopathy
|
N/A | |
Active, not recruiting |
NCT05556343 -
A Study to Evaluate the Efficacy, Safety, and Tolerability of MYK-224 in Participants With Symptomatic Obstructive Hypertrophic Cardiomyopathy
|
Phase 2 | |
Completed |
NCT03450252 -
Pacemaker Therapy for Drug-refractory Symptoms in Mid-cavity Hypertrophic Cardiomyopathy
|
N/A |