Cardiomyopathy, Dilated Clinical Trial
Official title:
Cell Therapy in Dilated Cardiomyopathy: A Safety and Feasibility Study Using Autologous Bone Marrow Mononuclear Cells
Verified date | January 2008 |
Source | Ministry of Health, Brazil |
Contact | n/a |
Is FDA regulated | No |
Health authority | Brazil: Ministry of Health |
Study type | Observational |
Using bone marrow mononuclear cell in 24 patients with Idiopathic dilated cardiomyopathy
Status | Terminated |
Enrollment | 24 |
Est. completion date | August 2007 |
Est. primary completion date | August 2006 |
Accepts healthy volunteers | No |
Gender | Both |
Age group | 18 Years to 70 Years |
Eligibility |
Inclusion Criteria: - Diagnosis of idiopathic dilated cardiomyopathy - Optimized therapy and for idiopathic dilated cardiomyopathy - Left ventricular ejection fraction (Simpson) < 35% - Peak oxygen consumption (VO2 peak) < 16 mL.kg-1min-1 - Functional classes II-IV of the NYHA Exclusion Criteria: - dilated cardiopathies of ischemic or chagasic origin - primary valve disease - excessive use of alcohol or illicit drugs - pregnancy - ventricular arrhythmias - any co-morbidity with impact on survival |
Observational Model: Case-Only, Time Perspective: Prospective
Country | Name | City | State |
---|---|---|---|
Brazil | INCL - National Institute of Cardiology Laranjeiras | Rio de Janeiro |
Lead Sponsor | Collaborator |
---|---|
Ministry of Health, Brazil |
Brazil,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | echocardiography | 2 months | No |
Status | Clinical Trial | Phase | |
---|---|---|---|
Active, not recruiting |
NCT03560167 -
Early Feasibility Study of the AccuCinch® Ventricular Restoration System in Patients With Prior Mitral Valve Intervention (PMVI) and Recurrent Mitral Regurgitation
|
N/A | |
Terminated |
NCT00624520 -
Mental Stress Reduction in Defibrillator Patients
|
Phase 3 | |
Completed |
NCT00549861 -
Characterization of Irreversible Myocardial Injury in Cardiomyopathies by Contrast-enhanced CMR
|
N/A | |
Terminated |
NCT04222101 -
Association of Insulin Resistance and FGF21 on Cardiac Function in Pediatric Dilated Cardiomyopathy
|
N/A | |
Not yet recruiting |
NCT02517814 -
Vitamin D Supplementation Can Improve Heart Function in Idiopathic Cardiomyopathy
|
N/A | |
Completed |
NCT01940081 -
The Leiden Nonischemic Cardiomyopathy Study
|
||
Completed |
NCT01391507 -
Pilot Study of COR-1 in Heart Failure
|
Phase 2 | |
Completed |
NCT01181414 -
Spanish Atrial Fibrillation And Resynchronization Study
|
Phase 4 | |
Not yet recruiting |
NCT06091475 -
Therapy to Maintain Remission in Dilated Cardiomyopathy
|
N/A | |
Recruiting |
NCT03340675 -
Oral Ifetroban in Subjects With Duchenne Muscular Dystrophy
|
Phase 2 | |
Recruiting |
NCT05981092 -
A Study About the Natural History in Adults With BAG3 Dilated Cardiomyopathy (a Type of Heart Disease)
|
||
Not yet recruiting |
NCT06039072 -
Clinical Observation of Long-term Cardiac Function Prognosis in Patients With PPCM Who Have Recovered Cardiac Function
|
||
Recruiting |
NCT03910725 -
Electrophysiological Phenotyping Of Patients at Risk of Ventricular Arrhythmia and Sudden Cardiac Death
|
||
Terminated |
NCT01478087 -
Immunoadsorption Therapy for Patients With Non-Ischemic Dilated Cardiomyopathy (DCM)
|
N/A | |
Recruiting |
NCT00221780 -
Role of Left Ventricular Pacing Site
|
N/A | |
Terminated |
NCT02958098 -
My Research Legacy Pilot Study
|
||
Completed |
NCT00123071 -
Variability of Ventricular Mass, Volume, & Ejection Fraction in Pediatric Cardiomyopathy Patients-Pediatric Heart Network
|
N/A | |
Completed |
NCT00284713 -
Progenitor Cell Therapy in Dilative Cardiomyopathy
|
Phase 1/Phase 2 | |
Completed |
NCT01260402 -
Randomized Comparison of Endocardial Versus Epicardial - From the Coronary Sinus - Left Ventricular Pacing for Resynchronization in Heart Failure.
|
N/A | |
Completed |
NCT04192214 -
The Persistence of Autoantibody Neutralisation by BC 007 in Patients With Chronic HFrEF and Autoantibodies Against the Beta1-Adrenergic Receptor
|
Phase 2 |