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Clinical Trial Summary

People aged over 75 represent almost 10% of the general population, and 12 to 14% of patients consulting emergency departments. Cardiogenic acute pulmonary edema (APO) is a very common reason for admission to the emergency room. The effectiveness of non-invasive ventilation (NIV) has been demonstrated during the management of PAO and would allow, compared to medical treatment alone, a more rapid improvement in clinical and gasometric parameters as well as a reduction in the need for ventilation. orotracheal intubation. On the other hand, the impact of NIV on mortality in cardiogenic PAO seems poorly defined, with lower levels of scientific evidence regarding a possible benefit in terms of survival, particularly in the elderly population. The objective of this study is to determine whether the use of NIV in cardiogenic PAO in elderly subjects admitted to the emergency room of Strasbourg University Hospital would have an impact in terms of mortality up to 6 months compared to medical treatment alone.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT06107257
Study type Observational
Source University Hospital, Strasbourg, France
Contact Elise SCHMITT, MD
Phone 33 3 88 11 58 84
Email elise.schmitt@chru-strasbourg.fr
Status Recruiting
Phase
Start date February 1, 2023
Completion date December 31, 2023

See also
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Completed NCT01680783 - Non-Invasive Ventilation Via a Helmet Device for Patients Respiratory Failure N/A
Completed NCT00785174 - Non-Invasive Ventilation Versus Continuous Positive Airway Pressure in Cardiogenic Pulmonary Edema: a Multicentre Study Phase 3
Completed NCT04005092 - Helmet CPAP Versus HFNC in Acute Cardiogenic Pulmonary Edema N/A
Completed NCT03041428 - Ultra Protective Ventilation During Venoarterial Extracorporeal Membrane Oxygenation (UPV-ECMO) N/A
Completed NCT00390442 - Out-of-Hospital CPAP for Severe Cardiogenic Pulmonary Edema Phase 3