Outcomes and Risk Factors of CPR in PICU

Cardio Respiratory Arrest Clinical Trial

Official title: Outcome of Cardiopulmonary Resuscitation in Tertiary Level PICU and Associated Risk Factors

Status Not yet recruiting

Clinical Trial Summary

1. To detect the frequency and the underlying causes of cardiopulmonary arrest .

2. To detect outcome of CPR

3. To identify the associated risk factors for the different outcomes after CPR among those patients

Clinical Trial Description

Cardiac arrest (CA) is uncommon in children, and the epidemiology of pediatric CA is different from adults. CA Is a critical cause of death in children in the hospital especially in the pediatric Intensive care unit (PICU). CA Is reported in 2-6% of children in the PICU, which is much higher than out-of-hospital arrest (about 8 to 20 annual cases per 100,000 pediatric population .

Previous studies reported that return of spontaneous circulation (ROSC) after cardiopulmonary Resuscitation (CPR) for in-hospital CA (IHCA) is about half of these patients, and ∼30% survived to hospital discharge Previous studies had analyzed the cause and prognostic factors associated with outcomes after IHCA, which included the Initial rhythm, duration of CA and CPR, the underlying disease, and where the event attacked .

Patients in PICU are more likely to develop CA because they are more critically ill. Information on factors associated with prognosis of in-PICU CA can promote Improvement in PICU care, which means improving survival with good neurologic outcomes .

Analyzing the epidemiological variables and risk/prognostic factors of in-PICU CA is of great Importance in developing the better therapeutic strategy and deciding appropriate preventive Measure .

Probability of death on admission and a longer length Of stay in the PICU were associated with increased odds of receiving CPR. Children admitted with cardiac conditions were at significantly higher risk of receiving CPR in the PICU Compared with those Admitted with noncardiac primary diagnosis. The risk Of receiving CPR was significantly associated with age, History of preadmission CPR, also, Electrolyte Imbalances and Multi-organ Dysfunction increase risk of receiving CPR in PICU . ;

Related Conditions & MeSH terms

• Cardio Respiratory Arrest

• NCT number: NCT06300710
• Study type: Observational
• Source: Assiut University
• Contact: Eman HK Khalaf, Resident physician
• Phone: +201111452811
• Email: emanh.khalaf1911@yahoo.com
• Status: Not yet recruiting
• Start date: April 1, 2024
• Completion date: March 1, 2025