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Clinical Trial Summary

This research study is about the effect heart-lung bypass procedures have on the vital organs (brain, heart, lungs, and kidneys) during open-heart surgery in pediatric patients. There are two types of heart pumps used in surgery requiring heart-lung bypass; one pumps the blood continuously through the body and the other pumps the blood with repeated pulses. Both pumps are approved for clinical use by the FDA. Although 90% of institutions still use non-pulsatile flow, some studies show there may be benefits to using pulsatile flow during surgery. The investigators want to learn whether the vital organs (brain, heart, lungs, and kidneys) respond differently to one method than they do to the other. Approximately 300 children will take part in this research at the Hershey Medical Center.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT00862407
Study type Observational
Source Milton S. Hershey Medical Center
Contact
Status Active, not recruiting
Phase
Start date October 2008
Completion date December 31, 2028

See also
  Status Clinical Trial Phase
Recruiting NCT05875272 - Interchangeability of Arterial Coagulation and Venous Coagulation, in the Context of Cardiac Surgeries Under Cardiopulmonary Bypass, Using the DMDiv Hemochron Signature Elite
Not yet recruiting NCT05079724 - Acute Kidney Injury After Cardiac Surgery
Completed NCT00048308 - Effect of Pexelizumab on All-Cause Mortality and Myocardial Infarction in Patients Undergoing Coronary Artery Bypass Graft Surgery With Cardio-Pulmonary Bypass Phase 3